Adrenal axis function does not appear to be associated with hemodynamic improvement in septic shock patients systematically receiving glucocorticoid therapy

J Morel, C Venet, Y Donati, D Charier, J Liotier… - Intensive care …, 2006 - Springer
Objective There is mounting evidence showing the value of low-dose corticosteroids in
patients with septic shock requiring vasopressor therapy. It remains unclear whether adrenal …

Role of corticosteroids in septic shock

LD Burry, RS Wax - Annals of Pharmacotherapy, 2004 - journals.sagepub.com
OBJECTIVE To highlight the role of relative adrenal insufficiency in the outcome of critically
ill patients with sepsis and systematically review the literature regarding the use of …

Relative adrenal insufficiency as a predictor of disease severity, mortality, and beneficial effects of corticosteroid treatment in septic shock

MFC De Jong, A Beishuizen, JJ Spijkstra… - Critical care …, 2007 - journals.lww.com
Objective: To evaluate the concept of relative adrenal insufficiency necessitating
corticosteroid therapy in septic shock. Design: Retrospective study. Setting: Medical-surgical …

Adrenocortical function during septic shock

G Bouachour, P Tirot, JP Gouello, E Mathieu… - Intensive care …, 1995 - Springer
Objective To investigate, in patients with severe septic shock, the adrenocortical function
assessed by daily plasma cortisol determinations during the first 72 h and by the short …

Sick adrenal or sick euadrenal?

B Venkatesh, J Cohen - Critical Care and Resuscitation, 2009 - Elsevier
The role of glucocorticoid supplementation in septic shock remains contentious. In septic
shock, the driver for steroid therapy is the premise that there is relative adrenal insufficiency …

Adrenal exhaustion in septic patients with vasopressor dependency

JA Guzman, CB Guzman - Journal of critical care, 2007 - Elsevier
PURPOSE: The use of low-dose corticosteroids for patients with septic shock who remain
vasopressor dependent after adequate fluid resuscitation is recommended, but there is lack …

An update on the diagnosis of adrenal insufficiency and the use of corticotherapy in critical illness

Z Thomas, GL Fraser - Annals of Pharmacotherapy, 2007 - journals.sagepub.com
Objective: To examine recent literature regarding corticotherapy in critically ill patients
suffering from sepsis, acute respiratory distress syndrome (ARDS), and severe community …

Glucocorticoid sensitivity is highly variable in critically ill patients with septic shock and is associated with disease severity

J Cohen, CJ Pretorius, JPJ Ungerer… - Critical Care …, 2016 - journals.lww.com
Objectives: To measure tissue glucocorticoid sensitivity in patients with septic shock and
determine its relationship to standard measurements of adrenal function and of outcome …

A single adrenocorticotropic hormone stimulation test does not reveal adrenal insufficiency in septic shock

P Loisa, A Uusaro, E Ruokonen - Anesthesia & Analgesia, 2005 - journals.lww.com
IMPLICATIONS: In this prospective study two consecutive adrenocorticotropic hormone
(ACTH) stimulation tests were performed in 60 critically ill patients. In a subgroup of septic …

[引用][C] Hydrocortisone and the reduction of vasopressors in septic shock: therapy or only chart cosmetics?

J Briegel - Intensive care medicine, 2000 - Springer
Intensive Care Med 2000) 26: 1723±1726 DOI 10.1007/s001340000736 EDITORIAL for its
assessment. However, the appropriate cutoff value for the diagnosis of relative …