Lipid‐based nanotherapeutics for siRNA delivery
A Schroeder, CG Levins, C Cortez… - Journal of internal …, 2010 - Wiley Online Library
RNA interference (RNAi) is a specific gene‐silencing mechanism triggered by small
interfering RNA (siRNA). The application of RNAi in the clinic requires the development of …
interfering RNA (siRNA). The application of RNAi in the clinic requires the development of …
Hybrid lipid–polymer nanoparticles for sustained siRNA delivery and gene silencing
The development of controlled-release nanoparticle (NP) technologies has great potential to
further improve the therapeutic efficacy of RNA interference (RNAi), by prolonging the …
further improve the therapeutic efficacy of RNA interference (RNAi), by prolonging the …
Dendrimers as carriers for siRNA delivery and gene silencing: a review
J Wu, W Huang, Z He - The Scientific World Journal, 2013 - Wiley Online Library
RNA interference (RNAi) was first literaturally reported in 1998 and has become rapidly a
promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small …
promising tool for therapeutic applications in gene therapy. In a typical RNAi process, small …
siRNA drug delivery across the blood–brain barrier in Alzheimer's disease
MI Sajid, FS Sheikh, F Anis, N Nasim… - Advanced Drug Delivery …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a few FDA-
approved drugs that provide modest symptomatic benefits and only two FDA-approved …
approved drugs that provide modest symptomatic benefits and only two FDA-approved …