Identifying essential proteins from active PPI networks constructed with dynamic gene expression
Essential proteins are vitally important for cellular survival and development, and identifying
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
A novel essential protein identification method based on PPI networks and gene expression data
J Zhong, C Tang, W Peng, M Xie, Y Sun, Q Tang… - BMC …, 2021 - Springer
Background Some proposed methods for identifying essential proteins have better results by
using biological information. Gene expression data is generally used to identify essential …
using biological information. Gene expression data is generally used to identify essential …
Identifying essential proteins based on dynamic protein-protein interaction networks and RNA-Seq datasets
X Shang, Y Wang, B Chen - Science China Information Sciences, 2016 - Springer
The identification of essential proteins is not only important for understanding organism
structure on the molecular level, but also beneficial to drug-target detection and genetic …
structure on the molecular level, but also beneficial to drug-target detection and genetic …
A new method for the discovery of essential proteins
Background Experimental methods for the identification of essential proteins are always
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
Detecting essential proteins based on network topology, gene expression data, and gene ontology information
W Zhang, J Xu, Y Li, X Zou - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
The identification of essential proteins in protein-protein interaction (PPI) networks is of great
significance for understanding cellular processes. With the increasing availability of large …
significance for understanding cellular processes. With the increasing availability of large …
A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data
Background Identification of essential proteins is always a challenging task since it requires
experimental approaches that are time-consuming and laborious. With the advances in high …
experimental approaches that are time-consuming and laborious. With the advances in high …
Prediction of essential proteins using topological properties in GO-pruned PPI network based on machine learning methods
W Kim - Tsinghua Science and Technology, 2012 - ieeexplore.ieee.org
The prediction of essential proteins, the minimal set required for a living cell to support
cellular life, is an important task to understand the cellular processes of an organism. Fast …
cellular life, is an important task to understand the cellular processes of an organism. Fast …
Essential protein detection by random walk on weighted protein-protein interaction networks
B Xu, J Guan, Y Wang, Z Wang - IEEE/ACM Transactions on …, 2017 - ieeexplore.ieee.org
Essential proteins are critical to the development and survival of cells. Identification of
essential proteins is helpful for understanding the minimal set of required genes in a living …
essential proteins is helpful for understanding the minimal set of required genes in a living …
Identification of essential proteins based on ranking edge-weights in protein-protein interaction networks
Essential proteins are those that are indispensable to cellular survival and development.
Existing methods for essential protein identification generally rely on knock-out experiments …
Existing methods for essential protein identification generally rely on knock-out experiments …
A topology potential-based method for identifying essential proteins from PPI networks
Essential proteins are indispensable for cellular life. It is of great significance to identify
essential proteins that can help us understand the minimal requirements for cellular life and …
essential proteins that can help us understand the minimal requirements for cellular life and …