A series of novel hybrid compounds of hexahydrobenzo [4, 5] thieno [2, 3-d] pyrimidine with
aminothiazole scaffolds were synthesized. The synthesized compounds were evaluated for …

This context deals with the design and synthesis of a new set of derivatives containing
thiazole, thiophene, and thieno [2, 3-d] pyrimidine motifs 3-13 starting with 2-((2 …

Abstract Two series of thieno [3, 2-d] pyrimidine derivatives containing diaryl urea moiety
were designed, synthesized and evaluated for their biological activity. The preliminary …

A series of novel thieno [3, 2-d] pyrimidine derivatives possessing diaryl semicarbazone
scaffolds were designed, synthesized and evaluated for their anticancer activity. Most …

Many literature reports revealed the anticancer activity of pyridine and thiazole derivatives,
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …

Novel pyridine-thiazole hybrid molecules were synthesized and subjected to physico-
chemical characterization and screening of their cytotoxic action towards a panel of cell lines …

A series of novel benzothiazole-2-thiol derivatives were synthesized and their structures
determined by 1H-NMR, 13C-NMR and HRMS (ESI). The effects of all compounds on a …

Background: Cancer is second leading disease after cardiovascular disease. Presently,
Chemotherapy, Radiotherapy and use of chemicals are some treatments available these …

Abstract A novel series of 1-(5-(benzylthio)-1, 3, 4-thiadiazol-2-yl)-3-phenylurea derivatives
(5a–l) were designed and synthesized as sorafenib analogs. The in vitro cytotoxicity effects …

Background Thiazole and thiosemicarbazone derivatives are known to have potential
anticancer activity with a mechanism of action related to inhibition of matrix metallo …