Behavioral and psychological symptoms in Alzheimer's disease

XL Li, N Hu, MS Tan, JT Yu… - BioMed research …, 2014 - Wiley Online Library
Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis
are now recognized as core features of Alzheimer's disease (AD), and there is a general …

Behavioral and psychiatric symptoms of dementia and rate of decline in Alzheimer's disease

RT Gottesman, Y Stern - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer's disease causes both cognitive and non-cognitive symptoms. There is increasing
evidence that the presentation and course of Alzheimer's disease is highly heterogenous …

Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future

YE Geda, LS Schneider, LN Gitlin, DS Miller… - Alzheimer's & …, 2013 - Elsevier
Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) are widespread and
disabling. This has been known since Dr. Alois Alzheimer's first case, Frau Auguste D …

Brain mechanisms underlying neuropsychiatric symptoms in Alzheimer's disease: a systematic review of symptom-general and–specific lesion patterns

Y Chen, M Dang, Z Zhang - Molecular Neurodegeneration, 2021 - Springer
Neuropsychiatric symptoms (NPSs) are common in patients with Alzheimer's disease (AD)
and are associated with accelerated cognitive impairment and earlier deaths. This review …

Understanding neuropsychiatric symptoms in Alzheimer's disease: challenges and advances in diagnosis and treatment

A Pless, D Ware, S Saggu, H Rehman… - Frontiers in …, 2023 - frontiersin.org
Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) affect up to 97% of AD
patients, with an estimated 80% of current AD patients experiencing these symptoms …

Neuropsychiatric disturbances in Alzheimer's disease: what have we learned from neuropathological studies?

DV Dam, Y Vermeiren, AD Dekker… - Current Alzheimer …, 2016 - ingentaconnect.com
Neuropsychiatric symptoms (NPS) are an integral part of the dementia syndrome and were
therefore recently included in the core diagnostic criteria of dementia. The near universal …

Neuropsychiatric symptoms predict functional status in Alzheimer's disease

SC You, CM Walsh, LA Chiodo… - Journal of …, 2015 - content.iospress.com
Background: Cognitive deficits are presumed to be the primary driver of functional
impairment in Alzheimer's disease (AD); however, functional impairment is likely …

Principles and management of neuropsychiatric symptoms in Alzheimer's dementia

MA Nowrangi, CG Lyketsos, PB Rosenberg - Alzheimer's research & …, 2015 - Springer
Neuropsychiatric symptoms of Alzheimer's disease (NPS-AD) are highly prevalent and lead
to poor medical and functional outcomes. In spite of the burdensome nature of NPS-AD, we …

The neurobiology of neuropsychiatric syndromes in dementia

TW Meeks, SA Ropacki, DV Jeste - Current opinion in psychiatry, 2006 - journals.lww.com
Neuropsychiatric disturbances are a core feature of dementia and worsen many clinical
outcomes. Among the most validated syndromes are depression, psychosis, and sleep …

Causal influences of neuropsychiatric disorders on Alzheimer's disease

A Baranova, Q Zhao, H Cao, V Chandhoke… - Translational …, 2024 - nature.com
Previous studies have observed a significant comorbidity between Alzheimer's disease (AD)
and some other neuropsychiatric disorders. However, the mechanistic connections between …