This brief article provides an overview of the current state of the art in biological imaging
mass spectrometry using cluster time-of-flight secondary ion mass spectrometry (TOF …

Fundamental advances in secondary ion mass spectrometry (SIMS) now allow for the
examination and characterization of lipids directly from biological materials. The successful …

Recent developments in instrumentation, ion beams or analyzers, for cluster time‐of‐flight
secondary ion mass spectrometry (TOF‐SIMS) imaging are described here. The methods …

Imaging by secondary ion mass spectrometry coupled to time-of-flight mass analysis (TOF-
SIMS) is a method of which the applications have greatly increased since 10 years. Taking …

Secondary ion mass spectrometry (SIMS) has been in use in biomedical imaging for more
than three decades and has resulted in some important biomedical discoveries. However …

Mass spectrometric imaging is a powerful tool to interrogate biological complexity. One such
technique, time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging, has been …

Recent technological and methodological improvements have greatly enhanced the
sensitivity of the Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS), thus making …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) can be utilized to map the
distribution of various molecules on a surface with submicrometer resolution. Much of its …

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) has unique capabilities in the
area of high-resolution mass spectrometric imaging of biological samples. The technique …

Time-of-flight secondary ion mass spectrometry (ToF–SIMS) imaging is an analytical
technique rapidly expanding in use in biological studies. This technique is based on high …