The look AHEAD trial: a review and discussion of its outcomes

X Pi-Sunyer - Current nutrition reports, 2014 - Springer
The Look AHEAD trial was a randomized controlled trial comparing an intensive lifestyle
intervention (ILI) to diabetes support and education (DSE) in overweight and obese type 2 …

The look AHEAD trial: implications for lifestyle intervention in type 2 diabetes mellitus

GR Dutton, CE Lewis - Progress in cardiovascular diseases, 2015 - Elsevier
Given the array of adverse health consequences of obesity, including increased risk for type
2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), the Look AHEAD trial (N …

Does lifestyle intervention improve health of adults with overweight/obesity and type 2 diabetes? Findings from the Look AHEAD randomized trial

RR Wing, Look AHEAD Research Group - Obesity, 2021 - Wiley Online Library
This paper reviews the main findings from the Action for Health in Diabetes (Look AHEAD)
Trial, a randomized trial testing the long‐term health effects of intensive lifestyle …

Aging and physical function in type 2 diabetes: 8 years of an intensive lifestyle intervention

WJ Rejeski, GA Bray, SH Chen, JM Clark… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Compared with adults without type 2 diabetes mellitus, those with the disease
experience more limitations in their physical functioning (PF). Look AHEAD is a large …

The development and description of the comparison group in the Look AHEAD trial

JA Wesche-Thobaben - Clinical trials, 2011 - search.proquest.com
Background Despite more lifestyle intervention trials, there is little published information on
the development of the comparison group intervention. This article describes the …

The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it

Look AHEAD Research Group - Obesity, 2006 - Wiley Online Library
Abstract The Look AHEAD (Action for Health in Diabetes) study is a multicenter, randomized
controlled trial designed to determine whether intentional weight loss reduces …

Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

Look AHEAD Research Group - New England journal of …, 2013 - Mass Medical Soc
Background Weight loss is recommended for overweight or obese patients with type 2
diabetes on the basis of short-term studies, but long-term effects on cardiovascular disease …

Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study

JM Jakicic, SA Jaramillo, A Balasubramanyam… - International Journal of …, 2009 - nature.com
Objective: To examine the effect of an intensive lifestyle weight loss intervention (ILI)
compared to diabetes support and education (DSE) on changes in fitness and physical …

Effects of intensive lifestyle intervention on all-cause mortality in older adults with type 2 diabetes and overweight/obesity: results from the Look AHEAD Study

Look AHEAD Research Group - Diabetes Care, 2022 - Am Diabetes Assoc
OBJECTIVE Look AHEAD, a randomized trial comparing intensive lifestyle intervention (ILI)
and diabetes support and education (DSE)(control) in 5,145 individuals with …

Eight‐year weight losses with an intensive lifestyle intervention: the look AHEAD study

Look AHEAD Research Group - Obesity, 2014 - Wiley Online Library
Objective To evaluate 8‐year weight losses achieved with intensive lifestyle intervention (ILI)
in the Look AHEAD (Action for Health in Diabetes) study. Design and Methods Look AHEAD …