Abstract Background Ocular rosacea (OcR) is a chronic inflammatory disease especially
affecting lid margins. Previous studies have shown that it is accompanied by increased …

Purpose Matrix metalloproteinases (MMPs) have a role in the pathogenesis of rosacea-
associated chronic blepharitis. Doxycycline is largely used as a treatment for recalcitrant …

purpose. To correlate tear fluorescein clearance with interleukin-1α (IL-1α) concentration
and gelatinase B (matrix metalloproteinase [MMP]-9) activity in the tear fluid of patients with …

purpose. To evaluate human corneal epithelial culture supernatant and tear fluid for the
presence of activators and inhibitors of matrix metalloproteinase (MMP)-9, MMP-3, and …

Aims: The purpose of this paper was to determine the lacrimal concentration of IL-1α and
MMP-9 in patients with active ocular rosacea before and after systemic treatment with …

Rosacea is a common skin disease that frequently involves the eye. Although the
pathogenesis of the disease remains undefined, recent findings suggest that an altered …

Purpose: To compare serum and tear inflammatory and anti-inflammatory cytokine levels of
rosacea patients with the healthy controls and evaluate the correlation of tear cytokine levels …

Purpose: To determine the concentration of interleukins (IL-1β and-6) and matrix
metalloproteinase 9 (pro-MMP-9) in the tears of patients with different ocular surface …

Background/aims: Orally administered doxycycline, a broad-spectrum antibiotic, is an
established treatment for ocular surface diseases, particularly rosacea, meibomian gland …

The matrix metalloproteinases, MMP-2 and MMP-9, are known to be critical extracellular-
remodeling enzymes in wound healing and other diseases of the ocular surface. This study …