The alcohol dehydrogenase (ADH) family constitutes one of the key sets of enzymes
responsible for the oxidation of alcohol. The ADH4 gene, an important member of this family …

Attention-deficit/hyperactivity disorder, ADHD, is a common and highly heritable
neuropsychiatric disorder that is seen in children and adults. Although heritability is …

Alcohol metabolism is one of the biological determinants that could significantly be
influenced by genetic polymorphisms in alcohol-metabolism genes. Alcohol dehydrogenase …

The alcohol dehydrogenases (ADHs) and aldehyde dehydrogenases (ALDHs) that
metabolize ethanol are polymorphic. Different alleles encode subunits of the enzymes that …

Alcohol dependence (AD) is a complex disorder with environmental and genetic origins. The
role of two genetic variants in ALDH2 and ADH1B in AD risk has been extensively …

Alcohol dependence (AD) is a moderately heritable phenotype with a small number of
known risk genes mapped via linkage or candidate gene studies. We considered 313 males …

Background: Normative alcohol use (or drinking behavior) influences the risk of
cardiovascular disease in a multi-faceted manner. To identify susceptibility gene variants for …

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in
Yokohama, Japan. The chairs were CJ Peter Eriksson and Tatsushige Fukunaga. The …

Alcohol drinking habits and alcoholism are partly genetically determined. Alcohol is
degraded primarily by alcohol dehydrogenase (ADH) wherein genetic variation that affects …

Motivation Principal component analysis (PCA) is a crucial step in quality control of genomic
data and a common approach for understanding population genetic structure. With the …