Emerging treatment strategies for metastatic triple-negative breast cancer

LA Huppert, O Gumusay… - Therapeutic advances in …, 2022 - journals.sagepub.com
Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that is
often associated with an aggressive phenotype and a poor prognosis. Cytotoxic …

Novel Therapies for Metastatic Triple-Negative Breast Cancer: Spotlight on Immunotherapy and Antibody-Drug Conjugates.

A Nagayama, N Vidula, A Bardia - Oncology (08909091), 2021 - search.ebscohost.com
BACKGROUND: Triple-negative breast cancer (TNBC) is a biologically heterogeneous
disease that is often associated with worse outcomes compared with other subtypes such as …

Recent advances in targeted strategies for triple-negative breast cancer

S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

Addition of immunotherapy to chemotherapy for metastatic triple-negative breast cancer: A systematic review and meta-analysis of randomized clinical trials

X Huo, G Shen, Z Liu, Y Liang, J Li, F Zhao… - Critical Reviews in …, 2021 - Elsevier
Background One of the front treatment regimens used for metastatic triple-negative breast
cancer (mTNBC) is treatment with programmed death-1 (PD-1) or programmed death ligand …

Immunotherapy for metastatic triple negative breast cancer: current paradigm and future approaches

V Geurts, M Kok - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement In approximately 15–20% of the patients diagnosed with breast cancer, it
comprises the triple negative (TN) subtype, which until recently lacked targets for specific …

Immunotherapeutic approaches in triple-negative breast cancer: latest research and clinical prospects

J Stagg, B Allard - Therapeutic advances in medical …, 2013 - journals.sagepub.com
Triple-negative breast cancer (TNBC), as defined by the absence of estrogen receptor,
progesterone receptor and human epidermal growth factor receptor 2 expression, is a …

Evolving immunotherapeutic solutions for triple-negative breast carcinoma

S Wu, A Ge, X Deng, L Liu, Y Wang - Cancer Treatment Reviews, 2024 - Elsevier
Triple-negative breast carcinoma (TNBC) remains a formidable clinical hurdle owing to its
high aggressiveness and scant therapeutic options. Nonetheless, the evolving landscape of …

Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Immunotherapy for triple-negative breast cancer: Existing challenges and exciting prospects

H Jia, CI Truica, B Wang, Y Wang, X Ren… - Drug resistance …, 2017 - Elsevier
Patients with breast tumors that do not express the estrogen receptor, the progesterone
receptor, nor Her-2/neu are hence termed “triple negatives”, and generally have a poor …

Deciding on the best pharmacotherapy for advanced triple-negative breast cancer: expert guidance

C Corvaja, B Taurelli Salimbeni, E Nicolò… - Expert Opinion on …, 2022 - Taylor & Francis
Triple-negative breast cancer (TNBC) is a heterogeneous disease with a complex biology
and high metastatic potential, defined by negative immunohistochemistry (IHC) for hormonal …