Clinical trials of immunotherapy in triple-negative breast cancer

FM Howard, AT Pearson, R Nanda - Breast Cancer Research and …, 2022 - Springer
Purpose Immunotherapy has started to transform the treatment of triple-negative breast
cancer (TNBC), in part due to the unique immunogenicity of this breast cancer subtype. This …

Immunotherapy for triple negative breast cancer: How can pathologic responses to experimental drugs in early-stage disease be enhanced?

F Giugliano, C Valenza, P Tarantino… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The treatment landscape of early triple-negative breast cancer (TNBC) has
recently expanded after the Food and Drug Administration (FDA) approval of …

Immune checkpoint inhibitors in triple negative breast cancer: the search for the optimal biomarker

S Qureshi, N Chan, M George, S Ganesan… - Biomarker …, 2022 - journals.sagepub.com
Triple negative breast cancer (TNBC) is a high-risk and aggressive malignancy
characterized by the absence of estrogen receptors (ER) and progesterone receptors (PR) …

Clinical Characteristics Associated with Efficacy and Prognosis among Patients Treated with PD-1/PD-L1 Inhibitors for Early-stage Triple-negative Breast Cancers: A …

Y Wei, Y Wu, Y Luo, F Ma - Critical Reviews in Oncology/Hematology, 2024 - Elsevier
Objective To assess the efficacy of PD-1/PD-L1 inhibitors combined with chemotherapy for
early-stage triple-negative breast cancer (TNBC) patients with different clinical …

Emerging strategies for TNBC with early clinical data: new chemoimmunotherapy strategies

PE Hall, P Schmid - Breast Cancer Research and Treatment, 2022 - Springer
Purpose The use of immune checkpoint inhibitors in combination with chemotherapy for the
treatment of triple-negative breast cancer is becoming more widespread as efficacy data …

Investigational drug treatments for triple-negative breast cancer

C Damaskos, N Garmpis, A Garmpi… - Journal of personalized …, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer (BC) and
accounts for 10–20% of cases. Due to the lack of expression of several receptors, hormone …

Triple-negative breast cancer: a review of current curative intent therapies

I MacDonald, NA Nixon, OF Khan - Current Oncology, 2022 - mdpi.com
Breast cancer is the most commonly diagnosed malignancy in women, with triple-negative
breast cancer (TNBC) accounting for 10–20% of cases. Historically, fewer treatment options …

Triple negative breast cancer: updates on classification and treatment in 2021

M Bou Zerdan, T Ghorayeb, F Saliba, S Allam… - Cancers, 2022 - mdpi.com
Simple Summary Triple negative breast cancer (TNBC) represents 15 to 20% of all breast
cancers in the United States. The main treatment option remains chemotherapy, despite …

Emerging therapeutics for patients with triple-negative breast cancer

E Agostinetto, D Eiger, K Punie, E de Azambuja - Current oncology reports, 2021 - Springer
Purpose of review Triple negative breast cancer (TNBC) accounts for approximately 10–
15% of all breast cancers and it is associated with a poor prognosis. However, recent new …

Immunotherapy: The end of the" dark age" for metastatic triple‐negative breast cancer?

M Palleschi, R Maltoni, S Sarti, E Melegari… - The Breast …, 2020 - Wiley Online Library
The lack of effective therapies for metastatic triple‐negative breast cancer (mTNBC)
highlights the need for the development of novel treatment strategies. The cornerstone of …