Trans forming growth factor β (TGF-β) and related cytokines regulate cell fate by signalling
through two receptor serine kinases that act in sequence. Signalling by these receptors is …

Signal transduction by the TGF-β family involves sets of receptor serine/threonine kinases,
Smad proteins that act as receptor substrates, and Smad-associated transcription factors …

Transforming growth factor-β (TGFβ) superfamily members are a group of secreted
polypeptides that regulate a diverse array of developmental and biological processes …

The transforming growth factor β (TGF-β) family of growth factors control the development
and homeostasis of most tissues in metazoan organisms. Work over the past few years has …

During the past 10 years, it has been firmly established that Smad pathways are central
mediators of signals from the receptors for transforming growth factor β (TGF-β) superfamily …

Transforming growth factor-β (TGF-β) controls a wide range of cellular functions by activating
both SMADs and non-SMAD pathways. In different tissue or physiological environment …

Transforming growth factor-β (TGF-β) superfamily members signal via membrane-bound
heteromeric serine–threonine kinase receptor complexes. Upon ligand-binding, receptor …

Members of transforming growth factor β (TGF-β) family are potent regulators of multiple
cellular functions, including cell proliferation, differentiation, migration, organization, and …

Smads are pivotal intracellular nuclear effectors of transforming growth factor‐β (TGF‐β)
family members. Ligand‐induced activation of TGF‐β family receptors with intrinsic …

Transforming growth factor-β (TGF-β) represents an evolutionarily conserved family of
secreted polypeptide factors that regulate many aspects of physiological embryogenesis …