Smads are a class of proteins that function as intracellusive promoter sites. Thus, Smads
have been shown to lar signaling effectors for the TGF-ß superfamily of seact as transcription …

Transforming growth factor‐beta (TGF‐β) is an important growth inhibitor of epithelial cells,
and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to …

Smads are intracellular transducers for TGF‐β superfamily ligands, but little is known about
the mechanism by which complexes of receptor‐phosphorylated Smad2 and Smad4 …

Transforming growth factor‐β (TGF‐β) regulates a wide variety of cellular processes
including cell growth, apoptosis, differentiation, migration, and extracellular matrix …

Transforming growth factor-beta (TGFβ) is a key regulator of cell fate during embryogenesis
and has also emerged as a potent driver of the epithelial-mesenchymal transition during …

Bone Morphogenetic Proteins (BMPs) together with the Growth and Differentiation Factors
(GDFs) form the largest subgroup of the Transforming Growth Factor (TGF) β family and …

Transforming growth factor (TGF)-β stimulation leads to phosphorylation and activation of
Smad2 and Smad3, which form complexes with Smad4 that accumulate in the nucleus and …

Transforming growth factor-β (TGF-β) proteins regulate cell function, and have key roles in
development and carcinogenesis. The intracellular effectors of TGF-β signalling, the Smad …

The transforming growth factor–β (TGF-β) superfamily of secreted polypeptide growth factors
exerts extensive control over all aspects of development and homeostasis, and components …

Smad proteins are a family of highly conserved, intracellular proteins that signal cellular
responses downstream of transforming growth factor-β (TGF-β) family serine/threonine …