Time to re‐consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma

G Gandolfi, V Sancisi, S Piana… - International Journal of …, 2015 - Wiley Online Library
The BRAF V600E mutation, resulting from the BRAFT1799A transversion, is the most
common genetic mutation in papillary thyroid carcinoma (PTC), with a mean frequency close …

Targeting of the BRAF gene in papillary thyroid carcinoma

Y Li, M Nakamura, K Kakudo - Oncology reports, 2009 - spandidos-publications.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and
includes several histological variants. Patients suffering from PTC usually have a good …

Allele Percentage of the BRAF V600E Mutation in Papillary Thyroid Carcinomas and Corresponding Lymph Node Metastases: No Evidence for a Role in Tumor …

G Gandolfi, V Sancisi, F Torricelli… - The Journal of …, 2013 - academic.oup.com
Context: The relevance of the BRAF V600E mutation in papillary thyroid carcinoma (PTC) as
a negative prognostic factor is a subject of intense debate. This mutation has been …

Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: A meta‐analysis

JH Lee, ES Lee, YS Kim - Cancer, 2007 - Wiley Online Library
BACKGROUND. Numerous studies have investigated the clinical significance of BRAF
mutation in papillary thyroid carcinoma (PTC). However, there have been conflicting data on …

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …

Clinicopathologic Implications of the BRAFV600E Mutation in Papillary Thyroid Cancer: A Subgroup Analysis of 3130 Cases in a Single Center

JY Lim, SW Hong, YS Lee, BW Kim, CS Park… - Thyroid, 2013 - liebertpub.com
Background: The BRAF mutation has been shown to be associated with aggressive
clinicopathologic characteristics of papillary thyroid cancer (PTC). However, several studies …

Incidence of BRAF V600E mutation in patients with papillary thyroid carcinoma: a single-institution experience

S Kure, K Ishino, M Kudo, R Wada… - Journal of …, 2019 - journals.sagepub.com
Objective Papillary thyroid carcinoma (PTC) accounts for 95% of all thyroid carcinomas. PTC
is an epithelial tumor characterized by the proliferation of follicular cells with distinctive …

BRAF mutations in papillary thyroid carcinoma and emerging targeted therapies

GC Leonardi, S Candido… - Molecular …, 2012 - spandidos-publications.com
Papillary thyroid carcinoma (PTC) is the most common histotype among the thyroid cancer
types. Although PTC is a curable malignancy, many patients relapse after treatment. Thus …

Prognostic value of the BRAF V600E mutation in papillary thyroid carcinoma

G He, B Zhao, X Zhang, R Gong - Oncology letters, 2014 - spandidos-publications.com
The aim of the present study was to investigate the prevalence of the BRAF V600E mutation
in papillary thyroid carcinoma (PTC) and to determine the correlation between this mutation …

[HTML][HTML] BRAF V600E mutation correlates with aggressive clinico-pathological features but does not influence tumor recurrence in papillary thyroid carcinoma—10 …

N Tabriz, J Grone, V Uslar, A Tannapfel, D Weyhe - Gland Surgery, 2020 - ncbi.nlm.nih.gov
Background BRAF V600E mutation is common in papillary thyroid carcinoma (PTC) but its
prognostic value and influence on tumor recurrence is controversial. We investigated if …