Mechanisms of the hypotensive action of captopril in essential hypertension

SE Ustinova, IM Zhukova, IA Uchitel, EV Parfenova… - …, 1986 - europepmc.org
Captopril effects were studied in 27 patients with second-stage essential hypertension
following administration of a single 25 mg oral dose of the drug. Blood pressure (BP), blood …

Antihypertensive and hemodynamic effects of captopril in essential hypertension

E Valvo, G Previato, A Lupo, C Loschiavo, N Tessitore… - Curr Ther …, 1982 - hero.epa.gov
Abstract IPA COPYRIGHT: ASHP The effects of captopril, 150-500 mg daily, on blood
pressure and systemic hemodynamics were studied in 10 patients with mild to moderate …

Humoral and hemodynamic effects of increasing doses of captopril in patients with essential hypertension

P Sassano, R Pedrinelli, A Magagna… - The American Journal of …, 1982 - Elsevier
To compare the hemodynamic and humoral effects of increasing doses of captopril, blood
pressure, heart rate, plasma renin activity, plasma aldosterone and angiotensin-converting …

Dose response in captopril therapy of hypertension

P Lijnen, R Fagard, J Staessen… - Clinical …, 1980 - Wiley Online Library
Dose‐response curves of blood pressure and of the biochemical components of the renin‐
angiotensin‐aldosterone system were determined during long‐term treatment with captopril …

Dose dependency of captopril effects in severely hypertensive patients

JC Aldigier, PF Plouin, JM Alexandre… - Journal of …, 1981 - journals.lww.com
In a double-blind randomized study, the dose response to captopril was studied in 12
severely hypertensive patients whose blood pressure had been previously controlled by this …

Role of various vasodepressor systems in the acute hypotensive effect of captopril in man

P Lijnen, R Fagard, J Staessen, LJ Verschueren… - European journal of …, 1981 - Springer
The acute hypotensive effect of captopril 25 mg was investigated in 26 hypertensive patients
(11 with essential and 15 with renal arterial disease). Intra-arterial blood pressure was …

Captopril, an Orally Active Converting Enzyme Inhibitor, in the Treatment of Primary Hypertension: A Controlled Long‐Term Study with Reference to Initial Plasma …

BE Karlberg, J Asplund, OR Nilsson… - Acta Medica …, 1981 - Wiley Online Library
Captopril (SQ 14 225), an orally active inhibitor of angiotensin converting enzyme, was
evaluated in the treatment of primary (essential) hypertension in a placebo‐controlled long …

Haemodynamic and clinical effects of long-term treatment of essential hypertension with captopril

B Ricciardelli, M Volpe, B Trimarco… - European Heart …, 1983 - academic.oup.com
Captopril, an orally active inhibitor of angiotensin converting enzyme, was administered for
12 months to 20 patients with mild or moderate essential hypertension who initially …

CAPTOPRIL IN PRIMARY HYPERTENSION: Effects related to the renin‐angiotensin‐aldosterone and kallikrein‐kinin systems.

KP Öhman, BE Karlberg, OR Nilsson… - Acta Medica …, 1981 - Wiley Online Library
The effects of captopril (SQ 14.225), an orally active inhibitor of angiotensin converting
enzyme, were investigated in a dose titration study of primary hypertension. In 32 patients 4 …

Effectiveness of captopril in severe hypertension (author's transl)

F Elkik, A Monteiro, P Corvol, P Milliez - La Nouvelle Presse …, 1981 - europepmc.org
Fifteen patients with severe essential or renal hypertension were treated with captopril. In
thirteen, a single oral dose of 1 mg/kg produced a mean fall of 20.7+/-16.42 mmHg (18%) in …