Deep Learning Techniques to Characterize the RPS28P7 Pseudogene and the Metazoa-SRP Gene as Drug Potential Targets in Pancreatic Cancer Patients
The molecular explanation about why some pancreatic cancer (PaCa) patients die early and
others die later is poorly understood. This study aimed to discover potential novel markers …
others die later is poorly understood. This study aimed to discover potential novel markers …
A Novel Perspective on Genes Driving Metastatic Pancreatic Cancer Revealed by Single-cell RNA Sequencing
Background: Pancreatic ductal adenocarcinoma (PDAC) is formidable in its advanced,
metastatic stage. Aggressive spread of malignant cells from the pancreas to distant organs …
metastatic stage. Aggressive spread of malignant cells from the pancreas to distant organs …
[HTML][HTML] Construction of a pyroptosis-related genes signature to improve the prognostic prediction and therapeutic drugs selection in patients with pancreatic cancer
C Li, M Wang, J Wei, W Zhang, H Liu… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Background Effective prognostic assessment and appropriate drug selection are important
for the clinical management of pancreatic cancer (PaC). Here, we aimed to establish a …
for the clinical management of pancreatic cancer (PaC). Here, we aimed to establish a …
Pyroptosis-related genes regulate proliferation and invasion of pancreatic cancer and serve as the prognostic signature for modeling patient survival
W Song, Z Liu, K Wang, K Tan, A Zhao, X Li, Y Yuan… - Discover Oncology, 2022 - Springer
Objective Pancreatic ductal adenocarcinoma (PDAC) has high mortality and poor prognosis.
Pyroptosis can influence the prognosis of patients by regulating the proliferation, invasion …
Pyroptosis can influence the prognosis of patients by regulating the proliferation, invasion …
Five gene signatures were identified in the prediction of overall survival in resectable pancreatic cancer
C Wu, Z Wu, B Tian - BMC surgery, 2020 - Springer
Background Although genes have been previously detected in pancreatic cancer (PC),
aberrant genes that play roles in resectable pancreatic cancer should be further assessed …
aberrant genes that play roles in resectable pancreatic cancer should be further assessed …
Exploring the potential of pyroptosis-related genes in predicting prognosis and immunological characteristics of pancreatic cancer from the perspective of genome and …
J Zhang, X You, D Kang, G Zhou - Frontiers in Oncology, 2022 - frontiersin.org
Objective To probe into the role of pyroptosis-related genes in pancreatic carcinoma.
Methods Herein, we conducted a comprehensive bioinformatics analysis to evaluate tumor …
Methods Herein, we conducted a comprehensive bioinformatics analysis to evaluate tumor …
System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma
C Yan, Y Niu, F Li, W Zhao, L Ma - Journal of translational medicine, 2022 - Springer
Background Pancreatic adenocarcinoma (PAAD) is one of the most common malignant
tumors of the digestive tract. Pyroptosis is a newly discovered programmed cell death that …
tumors of the digestive tract. Pyroptosis is a newly discovered programmed cell death that …
Identification by genetic algorithm optimized back propagation artificial neural network and validation of a four-gene signature for diagnosis and prognosis of …
Background Although some improvements in the management of pancreatic cancer (PC)
have been made, no major breakthroughs in terms of biomarker discovery or effective …
have been made, no major breakthroughs in terms of biomarker discovery or effective …
Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: New sights to clinical decision-making
J Zhu, Y Shi, S Lan, J Wang, F Jiang, C Tang, Y Cai… - Apoptosis, 2023 - Springer
Recent studies have indicated that pyroptosis may participate in the regulation of
tumorigenesis and immune microenvironment. However, the role of pyroptosis-related …
tumorigenesis and immune microenvironment. However, the role of pyroptosis-related …
Identification of candidate diagnostic and prognostic biomarkers for pancreatic carcinoma
Y Cheng, K Wang, L Geng, J Sun, W Xu, D Liu… - …, 2019 - thelancet.com
Background Pancreatic carcinoma (PC) is one of the most aggressive cancers affecting
human health. It is essential to identify candidate biomarkers for the diagnosis and …
human health. It is essential to identify candidate biomarkers for the diagnosis and …
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