Orchestrating a biomarker panel with lncRNAs and mRNAs for predicting survival in pancreatic ductal adenocarcinoma

Y Wu, J Wei, Y Ming, Z Chen, J Yu… - Journal of cellular …, 2018 - Wiley Online Library
The low survival of patients with pancreatic ductal adenocarcinoma (PDAC) makes the
treatment of this disease one of the most challenging task in modern medicine. Here, by …

Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts

J Lyu, M Jiang, Z Zhu, H Wu, H Kang, X Hao, S Cheng… - Cell Genomics, 2024 - cell.com
Pancreatic cancer (PC) is the deadliest malignancy due to late diagnosis. Aberrant
alterations in the blood proteome might serve as biomarkers to facilitate early detection of …

Identification of a nine-gene signature and establishment of a prognostic nomogram predicting overall survival of pancreatic cancer

M Wu, X Li, T Zhang, Z Liu, Y Zhao - Frontiers in oncology, 2019 - frontiersin.org
Background: Pancreatic cancer is highly lethal and aggressive with increasing trend of
mortality in both genders. An effective prediction model is needed to assess prognosis of …

[HTML][HTML] Identification of hub genes correlated with the pathogenesis and prognosis in Pancreatic adenocarcinoma on bioinformatics methods

LE Shi, X Shang, KC Nie, ZQ Lin, M Wang… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Pancreatic adenocarcinoma (PC), is a type of digestive tract cancer with the
highest mortality all over the word, and its exact pathogenesis is not clear. Therefore, it is of …

How hsa‐miR‐495 performed in the tumorigenesis of pancreatic adenocarcinoma by bioinformatics analysis

Y Yang, Y Wang, S Liu, X Zhao, R Jia… - Journal of Cellular …, 2019 - Wiley Online Library
Introduction Pancreatic adenocarcinoma (PAAD) is one of the most fatal cancers in the world
for early metastasis, extensive invasion, and poor prognosis with a 5‐year survival rate less …

Pyroptosis regulators exert crucial functions in prognosis, progression and immune microenvironment of pancreatic adenocarcinoma: a bioinformatic and in vitro …

Z Bai, F Xu, X Feng, Y Wu, J Lv, Y Shi, H Pei - Bioengineered, 2022 - Taylor & Francis
Pyroptosis is an inflammatory programmed cell death, showing potentials to be a novel anti-
cancer approach. However, the roles of pyroptosis-related (PR) genes (PRGs) in pancreatic …

Prediction of survival and recurrence in patients with pancreatic cancer by integrating multi-omics data

B Baek, H Lee - Scientific reports, 2020 - nature.com
Predicting the prognosis of pancreatic cancer is important because of the very low survival
rates of patients with this particular cancer. Although several studies have used microRNA …

A novel and robust long noncoding RNA panel to predict the prognosis of pancreatic cancer

M Li, H Li, Q Chen, W Wu, X Chen, L Ran, G Si… - DNA and cell …, 2020 - liebertpub.com
Pancreatic cancer (PC) is one of the most lethal malignancies with an extremely poor
prognosis. In this study, we aim to construct a long noncoding RNA (lncRNA)-based panel …

Single-cell RNA transcriptome reveals the intra-tumoral heterogeneity and regulators underlying tumor progression in metastatic pancreatic ductal adenocarcinoma

Q Xu, S Chen, Y Hu, W Huang - Cell Death Discovery, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is the most frequent and aggressive pancreatic
tumor characterized by high metastatic risk and special tumor microenvironment. To …

Construction and validation of a novel cuproptosis-related long noncoding RNA signature for predicting the outcome of prostate cancer

S Jiang, Z Li, R Dou, Z Lin, J Zhang, W Zhang… - Frontiers in …, 2022 - frontiersin.org
Background: Prostate cancer (PCa) is one of the most common tumors of the urinary system.
Cuproptosis is a novel mode of controlled cell death that is related to the development of …