Oxidative stress in Alzheimer's disease: are we connecting the dots? Miniperspective

M Rosini, E Simoni, A Milelli, A Minarini… - Journal of medicinal …, 2014 - ACS Publications
Redox impairment is a prominent feature of Alzheimer's disease (AD). It has led to the
“oxidative stress hypothesis”, which proposes antioxidants as beneficial therapeutic tools in …

[HTML][HTML] Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Antioxidant approaches for the treatment of Alzheimer's disease

HP Lee, X Zhu, G Casadesus… - Expert review of …, 2010 - Taylor & Francis
Oxidative stress is an important factor, and one that acts in the earliest stages, of Alzheimer's
disease (AD) pathogenesis. The reduction of oxidative stress has been tested as a therapy …

Oxidative stress in Alzheimer's disease: should we keep trying antioxidant therapies?

MES Ferreira, AS de Vasconcelos… - Cellular and molecular …, 2015 - Springer
The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …

[HTML][HTML] Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

Antioxidant therapies for Alzheimer′ s disease

Y Feng, X Wang - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disease featuring
progressive impairments in memory, cognition, and behavior and ultimately leads to death …

[HTML][HTML] Future therapeutic perspectives into the Alzheimer's disease targeting the oxidative stress hypothesis

JP Teixeira, AA de Castro, FV Soares, EFF da Cunha… - Molecules, 2019 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease that is usually accompanied by
aging, increasingly being the most common cause of dementia in the elderly. This disorder …

[HTML][HTML] Naturally occurring antioxidant therapy in Alzheimer's disease

AE Collins, TM Saleh, BE Kalisch - Antioxidants, 2022 - mdpi.com
It is estimated that the prevalence rate of Alzheimer's disease (AD) will double by the year
2040. Although currently available treatments help with symptom management, they do not …

Alzheimer's disease and antioxidant therapy: how long how far?

J Teixeira, T Silva, PB Andrade… - Current medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) has become a health problem to societies worldwide affecting
millions of people. AD normally ensues in middle and late life but its specific cause remains …

Alzheimer's disease: redox dysregulation as a common denominator for diverse pathogenic mechanisms

R Von Bernhardi, J Eugenín - Antioxidants & redox signaling, 2012 - liebertpub.com
Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …