Curcumin and neurodegenerative diseases: a perspective
Introduction: Curcumin, a dietary polyphenol found in the curry spice turmeric, possesses
potent antioxidant and anti-inflammatory properties and an ability to modulate multiple …
potent antioxidant and anti-inflammatory properties and an ability to modulate multiple …
Curcumin as a potential treatment for Alzheimer's disease: a study of the effects of curcumin on hippocampal expression of glial fibrillary acidic protein
Y Wang, H Yin, L Wang, A Shuboy, J Lou… - The American journal …, 2013 - World Scientific
Curcumin, an agent traditionally utilized for its preventative action against tumorigenesis,
oxidation, inflammation, apoptosis and hyperlipemia, has also been used in the treatment of …
oxidation, inflammation, apoptosis and hyperlipemia, has also been used in the treatment of …
Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice
D Yanagisawa, NF Ibrahim, H Taguchi, S Morikawa… - Neurobiology of …, 2015 - Elsevier
Recent evidence supports the amyloid cascade hypothesis that a pathological change of
amyloid β (Aβ) in the brain is an initiating event in Alzheimer's disease (AD). Accordingly …
amyloid β (Aβ) in the brain is an initiating event in Alzheimer's disease (AD). Accordingly …
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
Alzheimer's disease (AD) involves amyloid β (Aβ) accumulation, oxidative damage, and
inflammation, and risk is reduced with increased antioxidant and anti-inflammatory …
inflammation, and risk is reduced with increased antioxidant and anti-inflammatory …
Post-ischemic brain neurodegeneration in the form of Alzheimer's disease proteinopathy: Possible therapeutic role of curcumin
R Pluta, W Furmaga-Jabłońska, S Januszewski… - Nutrients, 2022 - mdpi.com
For thousands of years, mankind has been using plant extracts or plants themselves as
medicinal herbs. Currently, there is a great deal of public interest in naturally occurring …
medicinal herbs. Currently, there is a great deal of public interest in naturally occurring …
Curcumin as prospective anti-aging natural compound: focus on brain
T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …
New promising therapeutic avenues of curcumin in brain diseases
Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
M Garcia‐Alloza, LA Borrelli, A Rozkalne… - Journal of …, 2007 - Wiley Online Library
Alzheimer's disease (AD) is characterized by senile plaques and neurodegeneration
although the neurotoxic mechanisms have not been completely elucidated. It is clear that …
although the neurotoxic mechanisms have not been completely elucidated. It is clear that …
Curcumin decreases amyloid-β peptide levels by attenuating the maturation of amyloid-β precursor protein
Alzheimer disease (AD) is a devastating neurodegenerative disease with no cure. The
pathogenesis of AD is believed to be driven primarily by amyloid-β (Aβ), the principal …
pathogenesis of AD is believed to be driven primarily by amyloid-β (Aβ), the principal …
Curcumin and its derivatives as theranostic agents in Alzheimer's disease: The implication of nanotechnology
Curcumin is a polyphenolic natural compound with diverse and attractive biological
properties, which may prevent or ameliorate pathological processes underlying age-related …
properties, which may prevent or ameliorate pathological processes underlying age-related …