System and method for time-related microscopy of biological organisms

T Olesen, MC Valvik, NA Larsen - US Patent 9,915,813, 2018 - Google Patents
The invention relates to a system and a method for determination of a value for at least one
parameter describing microbial activity of individual biological organisms in a liquid sample …

Real-time monitoring of single bacterium lysis and leakage events by chemiluminescence microscopy

Y Zhang, GJ Phillips, ES Yeung - Analytical chemistry, 2007 - ACS Publications
The small size of bacteria makes it difficult to study the biochemistry inside single cells. The
amount of material inside is limited; therefore, an ultrasensitive method is required to …

Scanning microscope

H Takaoka - US Patent 6,496,267, 2002 - Google Patents
A scanning microscope allowing fluorescence observation and morphological observation
to be simultaneously performed on the same region of interest and permitting both a …

Computer interfaced scanning fluorescence lifetime microscope applied to directed evolution

NWT Woodbury, BP Bowen, A Scruggs - US Patent 7,193,706, 2007 - Google Patents
This invention provides a method for Screening large num bers of individual cells or
colonies of cells using scanning microscopy coupled with fluorescence lifetime measure …

Making the most of fluorescence: fluorescence lifetime imaging microscopy and spectral imaging complement conventional techniques

L Sage - The Scientist, 2005 - go.gale.com
Most of this work involves intensity analysis, inferring the abundance of a protein or
magnitude of an event from the strength of the colon But fluorescent labels generate two …

Imaging of bacterial cells by fluorescence exclusion using scanning confocal laser microscopy

DE Caldwell, DR Korber, JR Lawrence - Journal of Microbiological Methods, 1992 - Elsevier
Attached bacterial cells, microcolonies and biofilms were studied using negative fluorescent
staining (fluorescence exclusion) in conjunction with scanning confocal laser microscopy …

Whole-body imaging of bacterial infection and antibiotic response

RM Hoffman, M Zhao - Nature Protocols, 2006 - nature.com
We describe imaging of green fluorescent protein (GFP)-expressing bacteria from outside
intact infected animals. This simple, non-intrusive technique can show in great detail the …

High-resolution imaging of the microbial cell surface

KW Kim - Journal of microbiology, 2016 - Springer
Microorganisms, or microbes, can function as threatening pathogens that cause disease in
humans, animals, and plants; however, they also act as litter decomposers in natural …

Method and device for identifying micro organisms

M Korkeamaki, J Vaahtovuo - US Patent App. 10/523,935, 2006 - Google Patents
The invention relates to a method and device for identifying at least one micro organism
and/or micro organism species and for measuring the portion of at least one micro organism …

Method of counting microorganisms and device for accomplishing the counting

T Takahashi - US Patent 6,385,272, 2002 - Google Patents
A filter on which living bacteria are captured is processed with an extraction reagent and a
luminescence reagent. The state of luminescence of the filter is photographed by a …