Pannexin2 (Panx2) is the largest of three members of the pannexin proteins. Pannexins are
topologically related to connexins and innexins, but serve different functional roles than …

Pannexins have been proposed to play a role in gap junctional intercellular communication
and as single-membrane channels, although many of their molecular characteristics differ …

Pannexins are newly discovered channel proteins expressed in many different tissues and
abundantly in the vertebrate central nervous system. Based on membrane topology, folding …

Pannexins are homologous to innexins, the invertebrate gap junction family. However,
mammalian pannexin1 does not form canonical gap junctions, instead forming hexameric …

The pannexin family of mammalian proteins, composed of Panx1, Panx2, and Panx3, has
been postulated to be a new class of single-membrane channels with functional similarities …

In less than a decade, a small family of channel-forming glycoproteins, named pannexins,
have captured the interest of many biologists, in large part due to their association with …

Pannexins are mammalian orthologs of innexins and have a predicted topological folding
pattern similar to that of connexins, except they are glycosylated. Rat pannexin1 is …

The mammalian pannexin family of channel‐forming proteins consisting of Panx1, Panx2,
and Panx3 has received considerable attention in the last 10 years given their newly …

Pannexins are mammalian orthologs of the invertebrate gap junction proteins innexins and
thus have been proposed to play a role in gap junctional intercellular communication …

Pannexins (Panx) are a class of integral membrane proteins that have been proposed to
exhibit characteristics similar to those of connexin family members. In this study, we utilized …