Pannexins (Panx) are proteins with a similar membrane topology to connexins, the integral
membrane protein of gap junctions. Panx1 channels are generally of major importance in a …

Pannexin1 (Panx1) channels release cytosolic ATP in response to signaling pathways.
Panx1 is highly expressed in the central nervous system. We used four antibodies with …

Until recently, members of the connexin gene family were believed to comprise the sole
molecular component forming gap junction channels in vertebrates. The recent discovery of …

Pannexins (Panx) constitute a new family of gap junction type proteins. Functional
expression in paired Xenopus oocytes indicated that pannexins are capable of forming …

Abstract Pannexin1 (Panx1) belongs to a class of vertebrate proteins that exhibits sequence
homology to innexins, the invertebrate gap junction proteins, and which also shares …

Pannexins (Panx) are proteins homologous to the invertebrate gap junction proteins called
innexins (Inx) and are traditionally described as transmembrane channels connecting the …

Pannexins are a family of integral membrane proteins with distinct post-translational
modifications, sub-cellular localization and tissue distribution. Panx1 is the most studied and …

Connexins had been considered to be the only class of the vertebrate proteins capable of
gap junction formation; however, new candidates for this function with no homology to …

Pannexins are a newly described family of proteins that may form gap junctions. We made
antisera against mouse pannexin1 (Panx1). HeLa cells expressing Panx1 have cell surface …

Pannexins (Panx1, 2, 3) are channel-forming glycoproteins expressed in mammalian
tissues. We previously reported that N-glycosylation acts as a regulator of the localization …