Ketoprofen is a widely used NSAID which incurs gastric mucosal damage. The high mobility
group Box 1 (HMGB1) protein is a DNA-binding protein which exerts robust inflammatory …

Background Deregulation in prostaglandin (PG) biosynthesis, severe oxidative stress,
inflammation and apoptosis contribute to the pathogenesis of nonsteroidal anti-inflammatory …

Gastric ulcer (GU) is a main threat to public health. 1-Deoxynojirimycin (DNJ) has
antioxidant and anti-inflammatory properties and may prevent GU but related mechanism …

Ethanol consumption is one of the common causative agents implicated in gastric ulcer
development. Oxidative stress plays a major role in the induction and development of gastric …

Aberration of the gastric mucosal barrier homeostasis circuit is one of the key features linked
to the onset of gastric ulcers (GU). This work aimed to inspect the gastroprotective influence …

Excessive drinking of alcohol has been frequently associated with gastric injury; however, its
underlying molecular mechanisms have been inadequately investigated. Methyl palmitate …

Nonsteroidal anti-inflammatory drug (NSAID)-induced mitochondrial oxidative stress (MOS)
is an important prostaglandin (PG)-independent pathway of the induction of gastric mucosal …

Gastric mucosal injury is caused by an imbalance between the mucosal defense and gastro-
irritants, leading to gastroenteritis. Diosgenin is a steroidal sapogenin found in the wild Yam …

Piper nigrum Linnaeus is often used as a treatment for chills, stomach diseases, and other
ailments. Piperine has many biological functions; however, its mechanism for preventing …

Mallotus oblongifolius (MO), which is rich in polyphenols, is a characteristic tea resource
with medicinal value. In this study, a total of 45 polyphenolic components of MO, including …