A major lung cancer susceptibility locus maps to chromosome 6q23–25

JE Bailey-Wilson, CI Amos, SM Pinney… - The American Journal of …, 2004 - cell.com
Lung cancer is a major cause of death in the United States and other countries. The risk of
lung cancer is greatly increased by cigarette smoking and by certain occupational …

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

T Truong, RJ Hung, CI Amos, X Wu… - Journal of the …, 2010 - academic.oup.com
Background Genome-wide association studies have identified three chromosomal regions
at 15q25, 5p15, and 6p21 as being associated with the risk of lung cancer. To confirm these …

[HTML][HTML] A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

MT Landi, N Chatterjee, K Yu, LR Goldin… - The american journal of …, 2009 - cell.com
Three genetic loci for lung cancer risk have been identified by genome-wide association
studies (GWAS), but inherited susceptibility to specific histologic types of lung cancer is not …

Familial lung cancer: genetic susceptibility and relationship to chronic obstructive pulmonary disease

AG Schwartz, JC Ruckdeschel - American journal of respiratory and …, 2006 - atsjournals.org
Lung cancer continues to be the leading cause of cancer death, and although most lung
cancer is attributable to cigarette smoking, underlying genetic susceptibility is suggested by …

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12. 12 and 22q12. 2 in Han Chinese

Z Hu, C Wu, Y Shi, H Guo, X Zhao, Z Yin, L Yang… - Nature …, 2011 - nature.com
Lung cancer is the leading cause of cancer-related deaths worldwide. To identify genetic
factors that modify the risk of lung cancer in individuals of Chinese ancestry, we performed a …

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Q Lan, CA Hsiung, K Matsuo, YC Hong, A Seow… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we
conducted a multistage genome-wide association study of lung cancer in Asian women who …

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population

K Shiraishi, H Kunitoh, Y Daigo, A Takahashi, K Goto… - Nature …, 2012 - nature.com
Lung adenocarcinoma is the most common histological type of lung cancer, and its
incidence is increasing worldwide. To identify genetic factors influencing risk of lung …

Fine Mapping of Chromosome 6q23-25 Region in Familial Lung Cancer Families Reveals RGS17 as a Likely Candidate Gene

M You, D Wang, P Liu, H Vikis, M James, Y Lu… - Clinical cancer …, 2009 - AACR
Purpose: We have previously mapped a major susceptibility locus influencing familial lung
cancer risk to chromosome 6q23-25. However, the causal gene at this locus remains …

Genome-wide association study of familial lung cancer

J Byun, AG Schwartz, C Lusk, AS Wenzlaff… - …, 2018 - academic.oup.com
To identify genetic variation associated with lung cancer risk, we performed a genome-wide
association analysis of 685 lung cancer cases that had a family history of two or more first or …

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

JD McKay, RJ Hung, Y Han, X Zong… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …