Dermatologic side effects associated with the epidermal growth factor receptor inhibitors

ALC Agero, SW Dusza, C Benvenuto-Andrade… - Journal of the American …, 2006 - Elsevier
Epidermal growth factor receptor (EGFR) inhibitors are associated with unique and dramatic
dermatologic side effects. Cetuximab, erlotinib, and gefitinib have been approved for …

Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management

JC Hu, P Sadeghi, LC Pinter-Brown, S Yashar… - Journal of the American …, 2007 - Elsevier
The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in
anticancer therapy has been motivated by their specificity for EGFR, which improves their …

[HTML][HTML] Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors

S Segaert, E Van Cutsem - Annals of oncology, 2005 - Elsevier
The last few years, new therapies targeting the epidermal growth factor receptor (EGFR)
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …

Skin toxicities associated with epidermal growth factor receptor inhibitors

T Li, R Perez-Soler - Targeted oncology, 2009 - Springer
The use of epidermal growth factor receptor (EGFR) inhibitors in several epithelial tumors
has increased considerably in recent years. Currently, they are approved in non-small cell …

Cutaneous side‐effects in patients on long‐term treatment with epidermal growth factor receptor inhibitors

A Osio, C Mateus, JC Soria, C Massard… - British Journal of …, 2009 - academic.oup.com
Background Acute and subacute cutaneous side‐effects of epidermal growth factor receptor
inhibitors (EGFRIs) are very frequent and well known. Much less is known about the chronic …

Cutaneous reactions to anticancer agents targeting the epidermal growth factor receptor: a dermatology-oncology perspective.

ME Lacouture, BL Melosky - Skin Therapy Letter, 2007 - europepmc.org
The epidermal growth factor receptor (EGFR) is often overexpressed or dysregulated in solid
tumors. Targeting the EGFR-mediated signaling pathway has become routine practice in the …

Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining?

R Peréz-Soler, L Saltz - Journal of Clinical Oncology, 2005 - ascopubs.org
The human epidermal growth factor receptor (HER1/EGFR) is dysregulated in many solid
tumors, making it an attractive target for anticancer therapy. A number of agents that target …

Epidermal growth factor receptor inhibitor–associated cutaneous toxicities: an evolving paradigm in clinical management

TJ Lynch Jr, ES Kim, B Eaby, J Garey, DP West… - The …, 2007 - academic.oup.com
Epidermal growth factor receptor inhibitors (EGFRIs) have demonstrated improved overall
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …

The management of skin reactions in cancer patients receiving epidermal growth factor receptor targeted therapies: Behandlung der Hautreaktionen bei EGFR …

S Segaert, J Tabernero, O Chosidow… - JDDG: Journal der …, 2005 - Wiley Online Library
The use of epidermal growth factor receptor (EGFR) inhibitors for the treatment of solid
tumours is increasing. However, the tolerability profile for EGFR‐inhibitors, such as the …

Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results

SL Boone, A Rademaker, D Liu, C Pfeiffer, DJ Mauro… - Oncology, 2008 - karger.com
Biologic agents targeting the epidermal growth factor receptor (EGFR) have emerged as a
robust treatment option for various solid tumors. Despite lower systemic side effects than …