Background. A household contact substudy was performed as part of a prospective, cohort
pertussis vaccine efficacy trial in Germany. Design. Infants received four doses of either the …

Background. The goal of the trial was to determine the efficacy of a multicomponent acellular
pertussis vaccine against Bordetella illnesses in comparison with a whole-cell product and …

Severe adverse events were evaluated in a comparative efficacy trial in Germany in infants
who received either the Lederle/Takeda acellular pertussis component DTP (DTaP) vaccine …

Minor adverse events were evaluated in a comparative efficacy trial in Germany in infants
who received either the Lederle/Takeda acellular pertussis component DTP (DTaP) vaccine …

In preparation for a large efficacy trial in Germany, a pilot study was initiated in December
1990. In this study 149 infants were enrolled; with double-blind randomization 75 received …

The objective of this open study was to monitor the long-term effectiveness of the Lederle-
Takeda diphtheria and tetanus toxoids and acellular pertussis antigen (s)(DTaP) vaccine …

Background. We estimated the vaccine effectiveness (VE) of tetanus-diphtheria-acellular
pertussis vaccine (Tdap) for preventing pertussis among adolescents during a statewide …

BACKGROUND AND OBJECTIVES: Pertussis incidence is increasing, possibly due to the
introduction of acellular vaccines, which may have decreased the durability of immune …

OBJECTIVE: To assess the risk of pertussis by time since vaccination in children in
Minnesota and Oregon who received 5 doses of acellular pertussis vaccines (DTaP) …

BACKGROUND: During the 1990s, the United States switched from combined diphtheria,
tetanus toxoids, whole-cell pertussis (DTwP) vaccines to combined acellular pertussis …