Neuropathology changed by 3- and 6-months low-level PM2.5 inhalation exposure in spontaneously hypertensive rats

HC Chuang, HC Chen, PJ Chai, HT Liao… - Particle and Fibre …, 2020 - Springer
Background Epidemiological evidence has linked fine particulate matter (PM 2.5) to
neurodegenerative diseases; however, the toxicological evidence remains unclear. The …

Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus

MW Chao, CH Yang, PT Lin, YH Yang… - Environmental …, 2017 - Wiley Online Library
ABSTRACT PM2. 5 travels along the respiratory tract and enters systemic blood circulation.
Studies have shown that PM2. 5 increases the incidence of various diseases not only in …

Exposure to different PM2. 5 extracts induces gliosis and changes behavior in male rats similar to autism spectrum disorders features

M Rahmatinia, A Mohseni-Bandpei, F Khodagholi… - Environmental …, 2024 - Elsevier
Epidemiological studies have documented that exposure to fine particulate matter (PM 2.5)
could affect neurodevelopment, thereby leading to autism spectrum disorders (ASD) …

Neurotoxicity of the air-borne particles: from molecular events to human diseases

F Liu, C Liu, Y Liu, J Wang, Y Wang, B Yan - Journal of Hazardous Materials, 2023 - Elsevier
Exposure to PM 2.5 is associated with an increased incidence of CNS diseases in humans,
as confirmed by numerous epidemiological studies. Animal models have demonstrated that …

Recent advances in understanding the mechanisms of PM2. 5-mediated neurodegenerative diseases

X Zhu, X Ji, Y Shou, Y Huang, Y Hu, H Wang - Toxicology Letters, 2020 - Elsevier
PM 2.5 particles are widely believed to be associated with respiratory and cardiovascular
diseases. However, recent studies have reported that PM 2.5 may be associated with …

Progress in Mechanisms, Pathways and Cohort Studies About the Effects of PM2.5 Exposure on the Central Nervous System

M Ye, J Yang, J Li, Y Wang, W Chen, L Zhu… - Reviews of …, 2023 - Springer
An increasing number of studies have shown that particulate matter (PM) exposure can
produce damaging effects on respiratory and cardiovascular systems, however, whether PM …

Ambient PM2.5-induced brain injury is associated with the activation of PI3K/AKT/FoxO1 pathway

L Song, K Pan, X Du, S Jiang, X Zeng, J Zhang… - … Science and Pollution …, 2021 - Springer
Abstract PM 2.5-related neurological and mental diseases, such as cognitive impairment
and stroke, tend to cause disability. Six-week-old male C57BL/6 mice were divided into 6 …

Neurodevelopmental toxicity induced by airborne particulate matter

M Shang, M Tang, Y Xue - Journal of Applied Toxicology, 2023 - Wiley Online Library
Airborne particulate matter (PM), the primary component associated with health risks in air
pollution, can negatively impact human health. Studies have shown that PM can enter the …

Experimental rodent models exposed to fine particulate matter (PM2. 5) highlighting the injuries in the central nervous system: A systematic review

APS Ferreira, JMO Ramos, GD Gamaro, A Gioda… - Atmospheric Pollution …, 2022 - Elsevier
Exposure to the air pollution represents a major health risk, particulate matter is referred as
harmful component of the environmental contamination. The central nervous system …

Direct contact with particulate matter increases oxidative stress in different brain structures

LS Fagundes, AS Fleck, AC Zanchi… - Inhalation …, 2015 - Taylor & Francis
Introduction: Several experimental and epidemiological studies have demonstrated the
neurological adverse effects caused by exposure to air pollution, specifically in relation to …