During early lactation, dairy cows experience a severe metabolic load often resulting in the
development of various diseases. The inevitable deficiency in nutrients and energy at the …

The transition from pregnancy to lactation is the most challenging period for high-producing
dairy cows. The liver plays a key role in biological adaptation during the peripartum. Prior …

The transition period from late pregnancy to early lactation is a vital time of the lifecycle of
dairy cows due to the marked metabolic challenges. Besides, the liver is the pivot point of …

The liver is the main metabolic organ coordinating the adaptations that take place during the
peripartal period of dairy cows. A successful transition into lactation, rather than …

Cows can live for over 20 years, but their productive lifespan averages only around 3 years
after first calving. Liver dysfunction can reduce lifespan by increasing the risk of metabolic …

Background A transcriptomic approach was used to evaluate potential interactions between
prepartum body condition score (BCS) and feeding management in the weeks before …

Background The liver is central to most economically important metabolic processes in
cattle. However, the changes in expression of genes that drive these processes remain …

Long-term molecular adaptations in liver from high-producing dairy cows are virtually
unknown. Liver from five Holstein cows was biopsied at− 65,− 30,− 14,+ 1,+ 14,+ 28, and+ …

Repeated measurements analysis of variance–simultaneous component analysis (ASCA)
has been developed to handle complex longitudinal omics datasets and combine novel …

Heat stress negatively affects cow performance, compromises immune function, and
increases susceptibility to metabolic disorders, particularly during the dry period and as …