Developing Genetically Encoded Optical Tools for Imaging Brain Circuits and Pharmacology
C Dong - 2023 - escholarship.org
The brain is an intricate organ that controls various functions, such as perception, behavior,
mood, and cognition, through interactions between neurons, astrocytes with …
mood, and cognition, through interactions between neurons, astrocytes with …
Genetically encoded fluorescent sensors for imaging neuronal dynamics in vivo
J Day‐Cooney, R Dalangin, H Zhong… - Journal of …, 2023 - Wiley Online Library
The brain relies on many forms of dynamic activities in individual neurons, from synaptic
transmission to electrical activity and intracellular signaling events. Monitoring these …
transmission to electrical activity and intracellular signaling events. Monitoring these …
Fluorescence imaging of neural activity, neurochemical dynamics, and drug-specific receptor conformation with genetically encoded sensors
C Dong, Y Zheng, K Long-Iyer… - Annual review of …, 2022 - annualreviews.org
Recent advances in fluorescence imaging permit large-scale recording of neural activity and
dynamics of neurochemical release with unprecedented resolution in behaving animals …
dynamics of neurochemical release with unprecedented resolution in behaving animals …
[HTML][HTML] Imaging neurotransmitter and neuromodulator dynamics in vivo with genetically encoded indicators
BL Sabatini, L Tian - Neuron, 2020 - cell.com
The actions of neuromodulation are thought to mediate the ability of the mammalian brain to
dynamically adjust its functional state in response to changes in the environment. Altered …
dynamically adjust its functional state in response to changes in the environment. Altered …
Real time monitoring of neuromodulators in behaving animals using genetically encoded indicators
GO Mizuno, EK Unger, L Tian - … of In Vivo Monitoring in Real …, 2019 - books.google.com
Behavior is driven by precise spatial and temporal patterns of neural activity. Understanding
how the brain processes these complex patterns requires large-scale recording and …
how the brain processes these complex patterns requires large-scale recording and …
Imaging voltage and brain chemistry with genetically encoded sensors and modulators
Neurons and glia are functionally organized into circuits and higher-order structures that
allow the precise information processing required for complex behaviors. To better …
allow the precise information processing required for complex behaviors. To better …
Voltage imaging to understand connections and functions of neuronal circuits
Understanding of the cellular mechanisms underlying brain functions such as cognition and
emotions requires monitoring of membrane voltage at the cellular, circuit, and system levels …
emotions requires monitoring of membrane voltage at the cellular, circuit, and system levels …
[HTML][HTML] Advances in engineering and application of optogenetic indicators for neuroscience
Our ability to investigate the brain is limited by available technologies that can record
biological processes in vivo with suitable spatiotemporal resolution. Advances in …
biological processes in vivo with suitable spatiotemporal resolution. Advances in …
[HTML][HTML] Probing neuronal activity with genetically encoded calcium and voltage fluorescent indicators
M Sakamoto, T Yokoyama - Neuroscience Research, 2024 - Elsevier
Monitoring neural activity in individual neurons is crucial for understanding neural circuits
and brain functions. The emergence of optical imaging technologies has dramatically …
and brain functions. The emergence of optical imaging technologies has dramatically …
[HTML][HTML] State of the art imaging of neurotransmission in animal models
T Patriarchi, A Beyeler - Journal of neuroscience methods, 2022 - ncbi.nlm.nih.gov
The wide range of nervous system functions underlying animal physiology and behaviors is
ultimately encoded by the coordinated activity of neural cells, chiefly neurons and astrocytes …
ultimately encoded by the coordinated activity of neural cells, chiefly neurons and astrocytes …
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