[HTML][HTML] The role of AMP-activated protein kinase in the cardiovascular system

D Nagata, Y Hirata - Hypertension Research, 2010 - nature.com
It has recently been recognized that adiponectin protects the vasculature and prevents
atherosclerotic change through AMP-activated protein kinase (AMPK) activation, and some …

Protective effects of AMP‐activated protein kinase in the cardiovascular system

Q Xu, LY Si - Journal of cellular and molecular medicine, 2010 - Wiley Online Library
Introduction• AMPK structure and function• Role of AMPK in the heart• Role of AMPK in
endothelial cells• Role of AMPK in vascular smooth muscle cells• Role of AMPK in vascular …

AMP-activated protein kinase: a key stress signaling pathway in the heart

LH Young, J Li, SJ Baron, RR Russell - Trends in cardiovascular medicine, 2005 - Elsevier
AMP-activated protein kinase (AMPK) is activated during exercise and ischemia and is
emerging as an important regulatory mechanism in the heart. AMPK promotes adenosine …

[HTML][HTML] A new constitutively active mutant of AMP-activated protein kinase inhibits anoxia-induced apoptosis of vascular endothelial cell

D Nagata, A Kiyosue, M Takahashi, H Satonaka… - Hypertension …, 2009 - nature.com
The inhibition of apoptotic changes in vascular endothelial cells is important for preventing
vascular damage from hypoxia. AMP-activated protein kinase (AMPK) has recently been …

Role of the α2-isoform of AMP-activated protein kinase in the metabolic response of the heart to no-flow ischemia

E Zarrinpashneh, K Carjaval… - American Journal …, 2006 - journals.physiology.org
AMP-activated protein kinase (AMPK) is a major sensor and regulator of the energetic state
of the cell. Little is known about the specific role of AMPKα2, the major AMPK isoform in the …

AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease

AKF Wong, J Howie, JR Petrie, CC Lang - Clinical science, 2009 - portlandpress.com
AMPK (AMP-activated protein kinase) is a heterotrimetric enzyme that is expressed in many
tissues, including the heart and vasculature, and plays a central role in the regulation of …

AMPK in cardiovascular diseases

EP Daskalopoulos, C Dufeys, C Beauloye… - AMP-activated Protein …, 2016 - Springer
This chapter summarizes the implication of AMP-activated protein kinase (AMPK) in the
regulation of various physiological and pathological cellular events of great importance for …

AMP‐activated protein kinase: a core signalling pathway in the heart

AS Kim, EJ Miller, LH Young - Acta physiologica, 2009 - Wiley Online Library
Over the past decade, AMP‐activated protein kinase (AMPK) has emerged as an important
intracellular signalling pathway in the heart. Activated AMPK stimulates the production of …

AMP-activated protein kinase: a stress-responsive kinase with implications for cardiovascular disease

C Li, JF Keaney Jr - Current opinion in pharmacology, 2010 - Elsevier
AMP-activated protein kinase (AMPK) was initially viewed as energy sensor and activated
by increased intracellular concentrations of AMP following nutrient deprivation …

AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart

J Li, EJ Miller, J Ninomiya-Tsuji, RR Russell III… - Circulation …, 2005 - Am Heart Assoc
AMP-activated protein kinase (AMPK) promotes glucose transport, maintains ATP stores,
and prevents injury and apoptosis during ischemia. AMPK has several direct molecular …