[PDF][PDF] The antioxidant effect of boron on oxidative stress and DNA damage in diabetic rats

FK Coban, R Liman, IH Cigerci, S Ince… - Fresenius Environ …, 2015 - researchgate.net
The aim of the study was the evaluation of the potentially antioxidant effect of boron against
streptozotocin (STZ)-induced diabetes in rats. Animals were allocated into 5 groups of 6 rats …

[HTML][HTML] Cytotoxic and apoptotic effects of the combination of borax (Sodium tetraborate) and 5-fluorouracil on DLD-1 human colorectal adenocarcinoma cell line

ÖF KIRLANGIÇ, KS Ecem, Ö Sema… - Turkish Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Colorectal cancer (CRC) remains a crucial health problem due to the toxicity of 5-
Fluorouracil (5-FU) as first-line chemotherapy agent for treating CRC. The anticancer effects …

Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression

A Kinoshita, H Wanibuchi, K Morimura, M Wei… - …, 2003 - academic.oup.com
Our recent research indicated that phenobarbital (PB) may inhibit the development of N-
diethylnitrosamine (DEN)-initiated pre-neoplastic lesions at low doses in a rat liver medium …

Black tea polyphenols target matrix metalloproteinases, RECK, proangiogenic molecules and histone deacetylase in a rat hepatocarcinogenesis model

RS Murugan, G Vinothini, Y Hara, S Nagini - Anticancer research, 2009 - ar.iiarjournals.org
Background: The aim of this study was to evaluate the chemopreventive effects of black tea
polyphenols (Polyphenon-B) on markers of invasion and angiogenesis during …

[HTML][HTML] Beta-hydroxybutyrate promotes proliferation, migration and stemness in a subpopulation of 5FU treated SW480 cells: evidence for metabolic plasticity in colon …

A Shakery, K Pourvali, A Ghorbani… - Asian Pacific journal …, 2018 - ncbi.nlm.nih.gov
Background: Beta-hydroxybutyrate (BHB) as a ketone body is the metabolic fuel in oxidative
phosphorylation pathway. So far the effects of BHB on the biology of tumor cells is …

Vanadium compounds discriminate hepatoma and normal hepatic cells by differential regulation of reactive oxygen species

Q Wang, TT Liu, Y Fu, K Wang, XG Yang - JBIC Journal of Biological …, 2010 - Springer
Our previous study indicated that vanadium compounds can block cell cycle progression at
the G1/S phase in human hepatoma HepG2 cells via a highly activated extracellular signal …

[HTML][HTML] Potential antioxidant role of tridham in managing oxidative stress against aflatoxin-B1-induced experimental hepatocellular carcinoma

V Ravinayagam, R Jaganathan… - International Journal of …, 2012 - hindawi.com
Hepatocellular carcinoma (HCC) is one of the most fatal cancers due to delayed diagnosis
and lack of effective treatment options. Significant exposure to Aflatoxin B 1 (AFB 1), a potent …

Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice

M Kawai, Y Saegusa, Y Dewa, J Nishimura… - Archives of …, 2010 - Springer
Piperonyl butoxide (PBO) is a pesticide synergist used with pyrethroids as a domestic
insecticide, and it acts as a non-genotoxic hepatocarcinogen in rats and mice. To clarify …

Therapeutic efficacy of kaempferol against AFB1 induced experimental hepatocarcinogenesis with reference to lipid peroxidation, antioxidants and biotransformation …

L Kulanthaivel, P Srinivasan, V Shanmugam… - … & Preventive Nutrition, 2012 - Elsevier
Abstract Kaempferol (3, 5, 7, 4′-tetrahydroxy flavone), a naturally occuring flavonoid,
distributed all over the world tremendously essential because of its biological and health …

[HTML][HTML] Protective role of boron on hepatotoxicity and oxidative stress induced by trichloroacetic acid

C Wang, Y Shi, W Gu, C Wang, Y Xu, L Li… - Environmental Sciences …, 2023 - Springer
We conducted a comprehensive investigation into the protective roles of boron (B) against
trichloroacetic acid (TCA)-induced hepatotoxicity by assessing TCA exposure in vivo and …