Trait-like impulsivity does not predict escalation of heroin self-administration in the rat
Rationale The neural and psychological mechanisms underlying vulnerability to drug
addiction are poorly understood. Although a number of animal models have been …
addiction are poorly understood. Although a number of animal models have been …
Unidirectional relationship between heroin self-administration and impulsive decision-making in rats
MC Schippers, R Binnekade, ANM Schoffelmeer… - …, 2012 - Springer
Rationale There is growing clinical evidence for a strong relationship between drug
addiction and impulsivity. However, it is not fully clear whether impulsivity is a pre-existing …
addiction and impulsivity. However, it is not fully clear whether impulsivity is a pre-existing …
High impulsivity predicting vulnerability to cocaine addiction in rats: some relationship with novelty preference but not novelty reactivity, anxiety or stress
Rationale Impulsivity is a vulnerability marker for drug addiction in which other behavioural
traits such as anxiety and novelty seeking ('sensation seeking') are also widely present …
traits such as anxiety and novelty seeking ('sensation seeking') are also widely present …
High impulsivity predicts relapse to cocaine-seeking after punishment-induced abstinence
BACKGROUND: Relapse is a hallmark feature of cocaine addiction and a main challenge
for treatment strategies. Human studies indicate a link between impulsivity and increased …
for treatment strategies. Human studies indicate a link between impulsivity and increased …
Trait impulsive choice predicts resistance to extinction and propensity to relapse to cocaine seeking: a bidirectional investigation
N Broos, L Diergaarde, ANM Schoffelmeer… - …, 2012 - nature.com
Despite the strong association between impulsivity and addiction in humans, it is still a
matter of debate whether impulsive choice predisposes to, or results from, drug …
matter of debate whether impulsive choice predisposes to, or results from, drug …
The role of impulsivity in relapse vulnerability
T Pattij, TJ De Vries - Current opinion in neurobiology, 2013 - Elsevier
Drug dependence in humans is often accompanied by behavioral disturbances such as
maladaptive levels of impulsivity. In turn, there is accumulating evidence from preclinical …
maladaptive levels of impulsivity. In turn, there is accumulating evidence from preclinical …
Dependent heroin use and associated risky behaviour: The role of rash impulsiveness and reward sensitivity
LO Dissabandara, NJ Loxton, SR Dias, PR Dodd… - Addictive …, 2014 - Elsevier
Impulsive temperament has long been considered as a risk factor for substance use
disorders (SUD). Considering the heterogeneity of impulsivity, a biologically-based 2-factor …
disorders (SUD). Considering the heterogeneity of impulsivity, a biologically-based 2-factor …
Trait differences in response to chronic nicotine and nicotine withdrawal in rats
KZ Kolokotroni, RJ Rodgers, AA Harrison - Psychopharmacology, 2014 - Springer
Introduction Understanding an individual's vulnerability to drug addiction has important
implications for the development of effective personal treatment plans. Although theories …
implications for the development of effective personal treatment plans. Although theories …
The role of impulsive behavior in drug abuse
JL Perry, ME Carroll - Psychopharmacology, 2008 - Springer
Background Impulsivity is a multifaceted construct that has recently been recognized as a
factor contributing to enhanced vulnerability to drug abuse. Objectives In the present review …
factor contributing to enhanced vulnerability to drug abuse. Objectives In the present review …
Impulsivity predicts the escalation of cocaine self-administration in rats
JJ Anker, JL Perry, LA Gliddon, ME Carroll - … Biochemistry and Behavior, 2009 - Elsevier
Impulsivity, as measured by the delay-discounting task, predicts the acquisition of cocaine
self-administration and reinstatement of cocaine seeking in rats. The purpose of this study …
self-administration and reinstatement of cocaine seeking in rats. The purpose of this study …