Balance deficit enhances anxiety and balance training decreases anxiety in vestibular mutant mice

S Shefer, C Gordon, KB Avraham, M Mintz - Behavioural brain research, 2015 - Elsevier
Abstract Treatment of anxiety disorders by either pharmacological or behavioral means is
applied with the intention to directly target the limbic system or high brain centers that down …

Progressive vestibular mutation leads to elevated anxiety

S Shefer, CR Gordon, KB Avraham, M Mintz - Brain research, 2010 - Elsevier
Anxiety disorders are among the most common mental disorders, and are comorbid with
balance disorders in a significant proportion of these individuals. Presently, it is unclear …

Mice with vestibular deficiency display hyperactivity, disorientation, and signs of anxiety

R Avni, T Elkan, AA Dror, S Shefer, D Eilam… - Behavioural brain …, 2009 - Elsevier
Previous studies revealed that vestibular cues are crucial for exploration in the absence of
visual cues. The working hypothesis of this study was, accordingly, that mice with vestibular …

Anxiety and otovestibular disorders: linking behavioral phenotypes in men and mice

AV Kalueff, K Ishikawa, AJ Griffith - Behavioural brain research, 2008 - Elsevier
Human anxiety and vestibular disorders have long been known to co-occur. Paralleling
human clinical and non-clinical data, mounting genetic, pharmacological and behavioral …

Balance control and posture differences in the anxious BALB/cByJ mice compared to the non anxious C57BL/6J mice

EM Lepicard, P Venault, F Perez-Diaz, C Joubert… - Behavioural brain …, 2000 - Elsevier
A relation between anxiety disorders and balance control dysfunctions has been observed
in many studies in humans. A mismatch in the integration of sensory inputs could trigger …

Posture and balance responses to a sensory challenge are related to anxiety in mice

EM Lepicard, P Venault, J Negroni, F Perez-Diaz… - Psychiatry …, 2003 - Elsevier
Anxiety disorders and balance disorders share common clinical features related to
perception such as spatial disorientation or dizziness. The search for the mechanism …

Balance training improves memory and spatial cognition in healthy adults

AK Rogge, B Röder, A Zech, V Nagel, K Hollander… - Scientific reports, 2017 - nature.com
Physical exercise has been shown to improve cognitive functions. However, it is still
unknown which type of exercise affects cognition. In the present study, we tested the …

Effects of bilateral vestibular deafferentation on anxiety-related behaviours in Wistar rats

Y Zheng, M Goddard, CL Darlington… - Behavioural brain research, 2008 - Elsevier
Despite frequent reports that patients with vestibular dysfunction exhibit an unusually high
incidence of anxiety disorders, few studies have investigated the emotional effects of …

Performance in anxiety and spatial memory tests following bilateral vestibular loss in the rat and effects of anxiolytic and anxiogenic drugs

Y Zheng, I Cheung, PF Smith - Behavioural Brain Research, 2012 - Elsevier
Vestibular dysfunction in humans is associated with anxiety and cognitive disorders.
However, various animal studies of the effects of vestibular loss have yielded conflicting …

Methods for Evaluating Gait Associated Dynamic Balance and Coordination in Rodents

AD Modi, A Parekh, ZH Patel - Behavioural Brain Research, 2023 - Elsevier
Balance is the dynamic and unconscious control of the body's centre of mass to maintain
postural equilibrium. Regulated by the vestibular system, head movement and acceleration …