The vital role of central executive network in brain age: evidence from machine learning and transcriptional signatures

K Fang, S Han, Y Li, J Ding, J Wu… - Frontiers in Neuroscience, 2021 - frontiersin.org
Recent studies combining neuroimaging with machine learning methods successfully infer
an individual's brain age, and its discrepancy with the chronological age is used to identify …

[HTML][HTML] Discovery of High-Risk Clinical Factors That Accelerate Brain Aging in Adults: A Population-Based Machine Learning Study

J Sun, L Wang, Y Gao, Y Hui, S Chen, S Wu, Z Wang… - Research, 2024 - spj.science.org
Introduction: Brain age prediction using neuroimaging data and machine learning
algorithms holds significant promise for gaining insights into the development of …

Predicting brain age using structural neuroimaging and deep learning

Y Varatharajah, S Baradwaj, A Kiraly, D Ardila, R Iyer… - BioRxiv, 2018 - biorxiv.org
Early detection of age-related diseases will greatly benefit from a model of the underlying
biological aging process. In this paper, we develop a brain-age predictor by using structural …

Estimating brain age based on a healthy population with deep learning and structural MRI

X Feng, ZC Lipton, J Yang, SA Small… - arXiv preprint arXiv …, 2019 - arxiv.org
Numerous studies have established that estimated brain age, as derived from statistical
models trained on healthy populations, constitutes a valuable biomarker that is predictive of …

Network occlusion sensitivity analysis identifies regional contributions to brain age prediction

L He, C Chen, Y Wang, Q Fan, C Chu, J Xu, L Fan - bioRxiv, 2022 - biorxiv.org
Deep learning frameworks utilizing convolutional neural networks (CNNs) have frequently
been used for brain age prediction and have achieved outstanding performance …

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

VM Bashyam, G Erus, J Doshi, M Habes, IM Nasrallah… - Brain, 2020 - academic.oup.com
Deep learning has emerged as a powerful approach to constructing imaging signatures of
normal brain ageing as well as of various neuropathological processes associated with …

Morphological brain age prediction using multi-view brain networks derived from cortical morphology in healthy and disordered participants

J Corps, I Rekik - Scientific reports, 2019 - nature.com
Brain development and aging are dynamic processes that unfold over years on multiple
levels in both healthy and disordered individuals. Recent studies have revealed a disparity …

[HTML][HTML] A deep neural network estimation of brain age is sensitive to cognitive impairment and decline

Y Yang, A Sathe, K Schilling, N Shashikumar… - …, 2023 - pmc.ncbi.nlm.nih.gov
The greatest known risk factor for Alzheimer's disease (AD) is age. While both normal aging
and AD pathology involve structural changes in the brain, their trajectories of atrophy are not …

Brain age estimation from MRI using cascade networks with ranking loss

J Cheng, Z Liu, H Guan, Z Wu, H Zhu… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Chronological age of healthy people is able to be predicted accurately using deep neural
networks from neuroimaging data, and the predicted brain age could serve as a biomarker …

[HTML][HTML] Improving brain age estimates with deep learning leads to identification of novel genetic factors associated with brain aging

K Ning, BA Duffy, M Franklin, W Matloff, L Zhao… - Neurobiology of …, 2021 - Elsevier
To study genetic factors associated with brain aging, we first need to quantify brain aging.
Statistical models have been created for estimating the apparent age of the brain, or …