Initially viewed as dangerous byproducts of aerobic life, reactive oxygen species (ROS)
nowadays appear to be essential secondary messengers of many signaling cascades and …

ROS (reactive oxygen species) have long been regarded as a series of destructive
molecules that have a detrimental effect on cell homoeostasis. In support of this are the …

Abstract Significance: Reduction/oxidation (redox) balance could be defined as an even
distribution of reduction and oxidation complementary processes and their reaction end …

Cell cycle regulation is performed by cyclins and cyclin dependent kinases (CDKs).
Recently, it has become clear that reactive oxygen species (ROS) influence the presence …

Angiogenesis is essential for tumor growth, metastasis, arteriosclerosis as well as embryonic
development and wound healing. Its process is dependent on cell proliferation, migration …

NADPH oxidases of the NADPH oxidase (NOX) family are dedicated reactive oxygen
species-generating enzymes that broadly and specifically regulate redox-sensitive …

The NADPH oxidase (Nox) family of enzymes generates reactive oxygen species (ROS). At
low ROS concentration, intracellular signaling is initiated, whereas at high ROS …

Significance: Reactive oxygen species (ROS) such as superoxide, hydrogen peroxide, and
peroxynitrite are generated ubiquitously by all mammalian cells and have been understood …

Reactive oxygen species (ROS) are associated with multiple cellular functions such as cell
proliferation, differentiation, and apoptosis. However, the direct roles of endogenous ROS …

Significance: Reactive oxygen species (ROS) promote genomic instability, altered signal
transduction, and an environment that can sustain tumor formation and growth. The NOX …