Article abstract The A1/A1 genotype of the anti-inflammatory cytokine interleukin 1 receptor
antagonist (IL-1Ra) polymorphism was more frequent in 339 Italian MS patients than in …

Objective: To investigate whether polymorphisms in the interleukin (IL)-1 β and IL-1 receptor
antagonist (IL-1RA) genes are associated with both susceptibility to and clinical …

Polymorphisms in the interleukin-1 genes, IL-1A and IL-1B, have been associated with AD,
but not in all studies. The authors genotyped the IL-1A (-889) and IL-1B (-511) …

Evidence of inflammatory phenomena associated with atherosclerotic plaques is extensive.
Interleukin-1 (IL-1) is one of the key modulators of the inflammatory response, and its activity …

Crusius and colleagues1 reported a positive association between allele 2 of the interleukin-
1 receptor antagonist (IL-1ra) gene which maps to 2q13–14 and multiple sclerosis (MS). Our …

We studied the putative association of a C→ T polymorphism in exon-5 of IL-1β and an 85
bp tandem repeat in intron-4 of IL-1 receptor antagonist (IL-1ra) genes with susceptibility to …

Background: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic
influence on susceptibility and disease course. Cytokines play an important role in MS …

A recent candidate gene study employing microsatellite markers suggested a possible
linkage of multiple sclerosis (MS) with the interleukin-4 receptor (IL4R) gene. Consequently …

We investigated the association of specific polymorphisms of the interleukin IL-1b (Ava I−
511 and Taq I+ 3,953) and IL-1 receptor antagonist (IL-1RN)(a variable number of tandem …

Methods. All patients with NMO fulfilled the 2006 Wingerchuk 5 criteria for NMO, while those
with NMO spectrum disorders who did not completely meet the criteria were excluded. All …