Time study on development and repair of lung injury following ozone exposure in rats
L van Bree, JAMA Dormans, AJF Boere, PJA … - Inhalation …, 2001 - Taylor & Francis
The aim of this study was to investigate the time course of lung injury in rats during acute
and subchronic ozone exposure and during postexposure recovery. Rats were continuously …
and subchronic ozone exposure and during postexposure recovery. Rats were continuously …
Interspecies differences in time course of pulmonary toxicity following repeated exposure to ozone
J Dormans, L Van Bree, AJF Boere, M Marra… - Inhalation …, 1999 - Taylor & Francis
To compare the extent and time course of pulmonary injury and repair in 3 rodent species,
rats, mice and guinea pigs were continuously exposed for 3, 7, 28, and 56 days to 400 and …
rats, mice and guinea pigs were continuously exposed for 3, 7, 28, and 56 days to 400 and …
Attenuation and recovery of pulmonary injury in rats following short-term, repeated daily exposure to ozone
L Bree, J Dormans, HS Koren, RB Devlin… - Inhalation …, 2002 - Taylor & Francis
Controlled human and epidemiology studies have demonstrated that during repeated
exposure to ozone (O 3) attenuation of lung function responses may occur. It is yet unknown …
exposure to ozone (O 3) attenuation of lung function responses may occur. It is yet unknown …
Pulmonary inflammation and epithelial injury in response to acute ozone exposure in the rat
MV Pino, JR Levin, MY Stovall, DM Hyde - Toxicology and applied …, 1992 - Elsevier
To document the time course of the inflammatory response and epithelial injury in the lung
following and acute ozone exposure, rats were exposed to 1.0 ppm ozone for periods …
following and acute ozone exposure, rats were exposed to 1.0 ppm ozone for periods …
Effects of Acute Exposure to O3 On Rats: Sequence of Epithelial and Inflammatory Changes in the Distal Airways
DK Bhalla, C Young - Inhalation toxicology, 1992 - Taylor & Francis
This study involves the analysis of the sequence of changes in lung epithelial permeability,
free cells in the airways, prostaglandin E2 (PGE2) levels, polymorphonuclear leukocyte …
free cells in the airways, prostaglandin E2 (PGE2) levels, polymorphonuclear leukocyte …
Functional and pathologic consequences of a 52-week exposure to 0.5 ppm ozone followed by a clean air recovery period
KB Gross, HJ White - Lung, 1987 - Springer
Male Fischer 344 rats were exposed to 0.5 ppm ozone for 20 hr/day, 7 days/week, for 52
weeks after which they were allowed to recover in clean filtered air for 12 weeks. Pulmonary …
weeks after which they were allowed to recover in clean filtered air for 12 weeks. Pulmonary …
Evolution of lung lesions in rats exposed to mixtures of ozone and nitrogen dioxide
CA Farman, KE Pinkerton, P Rajini, H Witschi… - Inhalation …, 1997 - hero.epa.gov
In previous work we have shown that rats exposed to 0.8 m ozone and 14.4 ppm NO2 for 6 h
daily develop progressive bronchiolitis and pulmonary fibrosis after about 8-10 wk of …
daily develop progressive bronchiolitis and pulmonary fibrosis after about 8-10 wk of …
Consequences of prolonged inhalation of ozone on F344/N rats: collaborative studies. Part VIII: Morphometric analysis of structural alterations in alveolar regions.
LY Chang, BL Stockstill, MG Menache… - … Report (Health Effects …, 1995 - europepmc.org
Morphometric techniques were used to examine cellular and tissue changes occurring in
male and female rat lungs exposed to ozone for a prolonged time. F344/N rats were …
male and female rat lungs exposed to ozone for a prolonged time. F344/N rats were …
Effect of low level of ozone on rat lungs: II. Morphological responses during recovery and re-exposure
CG Plopper, CK Chow, DL Dungworth… - Experimental and …, 1978 - Elsevier
Morphological studies were made of the effect of 0.8 ppm ozone on lungs of 70-day-old
male rats at the end of a 3-day exposure, after 6, 9, or 30 days of recovery, and at the end of …
male rats at the end of a 3-day exposure, after 6, 9, or 30 days of recovery, and at the end of …
[引用][C] A comprehensive ultrastructural study of pulmonary injury and repair in the rat resulting from exposures to less than one PPM ozone
RJ Stephens, MJ Evans, MF Sloan, G Freeman - Chest, 1974 - journal.chestnet.org
The purpose of this research is to describe the initial processes of injury and repair following
exposure to levels of ozone (Os) that often exist in the polluted air of major cities. Previous …
exposure to levels of ozone (Os) that often exist in the polluted air of major cities. Previous …
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