Activated hypothalamic pituitary adrenal axis in patients with metabolic syndrome

P Kazakou, V Kyriazopoulou… - Hormone and …, 2012 - thieme-connect.com
Metabolic syndrome (MetS) is correlated with the activity of hypothalamic-pituitary-adrenal
axis (HPA), but the underlying mechanism still remains elusive. The aim of this study was to …

Do depressed patients without activation of the hypothalamus–pituitary–adrenal (HPA) system have metabolic disturbances?

B Scharnholz, M Gilles, A Marzina, M Kommer… - …, 2014 - Elsevier
This study compared features of the metabolic syndrome between healthy controls and
depressed patients without activation of the hypothalamus–pituitary–adrenal (HPA) system …

Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal axis activity is associated with metabolic …

CMM Licht, SA Vreeburg… - The Journal of …, 2010 - academic.oup.com
Context: Stress is suggested to lead to metabolic dysregulations as clustered in the
metabolic syndrome, but the underlying biological mechanisms are not yet well understood …

Metabolic syndrome as a common comorbidity in adults with hypothalamic dysfunction

Z Xu, X Ke, X Yuan, L Wang, L Duan, Y Yao… - Frontiers in …, 2022 - frontiersin.org
Objective Hypothalamic dysfunction (HD) results in various endocrine disorders and is
associated with an increased risk of metabolic comorbidities. This study aimed to analyze …

Central hypothalamic-pituitary-adrenal activity and the metabolic syndrome: Studies using the corticotrophin-releasing hormone test

AMV Ward, HE Syddall, PJ Wood, EM Dennison… - Metabolism, 2004 - Elsevier
A number of studies have suggested that the metabolic syndrome (principally, the
combination of hypertension, glucose intolerance, and dyslipidemia) is associated with …

ACTH and cortisol response to combined corticotropin releasing hormone-arginine vasopressin stimulation in obese males and its relationship to body weight, fat …

R Pasquali, L Gagliardi, V Vicennati… - International journal of …, 1999 - nature.com
OBJECTIVES: To investigate the activity of the hypothalamic–pituitary–adrenal (HPA) axis in
male obesity and its relationship with several prominent parameters of the metabolic …

Cortisol in tissue and systemic level as a contributing factor to the development of metabolic syndrome in severely obese patients

P Constantinopoulos, M Michalaki… - European journal of …, 2015 - academic.oup.com
Context Adrenal and extra-adrenal cortisol production may be involved in the development
of metabolic syndrome (MetS). Objective To investigate the activity of the hypothalamic …

Hypothalamic–Pituitary–Adrenal (HPA) axis functioning in relation to body fat distribution

F Rutters, AG Nieuwenhuizen… - Clinical …, 2010 - Wiley Online Library
Objective To relate hypothalamic–pituitary–adrenal (HPA) axis functioning and HPA
feedback functioning to body fat distribution in normal weight to obese subjects. Patients 91 …

Altered response to neuroendocrine challenge linked to indices of the metabolic syndrome in healthy adults

AR Tyrka, OC Walters, LH Price… - Hormone and …, 2012 - thieme-connect.com
Metabolic syndrome (MetS) is characterized by central obesity, hypertension, insulin
resistance, and hypercholesterolemia. Hypothalamic-pituitary-adrenal (HPA) axis activity is …

[PDF][PDF] The effects of high fat diet on the basal activity of the hypothalamuspituitaryadrenal axis in mice

HE Auvinen, JA Romijn, NR Biermasz… - Journal of …, 2012 - researchgate.net
Alterations in hypothalamus–pituitary–adrenal (HPA) axis activity have been linked to the
development of the metabolic syndrome (MetS). Common features of the MetS, like insulin …