Dysfunction of cell bioenergetics is a common feature of neurodegenerative diseases, the
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …

Increasing evidences suggest that mitochondrial dysfunction plays an important role in the
pathogenesis of neurodegenerative diseases including Alzheimer's disease (AD) …

Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by the
progressive loss of cholinergic neurons, leading to the onset of severe behavioral, motor …

Abstract Alzheimer's disease (AD), the most common form of dementia, is thought to be
associated with multiple factors, where the greatest risk factor is aging. Several traditional …

Alzheimer's disease (AD) is one of the major reasons for 60-80% cases of senile dementia
occurring as a result of the accumulation of plaques and tangles in the hippocampal and …

Several studies have demonstrated aberrations in the Electron Transport Complexes (ETC)
and Krebs (TCA) cycle in Alzheimer's disease (AD) brain. Optimal activity of these key …

Mitochondria are dynamic ATP-generating organelle which contribute to many cellular
functions including bioenergetics processes, intracellular calcium regulation, alteration of …

Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

J. Neurochem.(2010) 114, 933–945. Abstract Despite the increasing knowledge of
Alzheimer's disease (AD) management with novel pharmacologic agents, most of them are …