Genomics and Epigenomics of Natural Killer/T Cell Lymphoma: Diagnostic, Prognostic, and Therapeutic Implications

Y Tan, C Küçük, L Cui - 2024 - Springer
Natural killer/T cell lymphoma (NKTCL), as an invasive subtype of non-Hodgkin lymphoma,
is tightly linked with Epstein-Barr virus (EBV) infection. Genomic and epigenomic aberrations …

[HTML][HTML] Genomic and transcriptomic characterization of natural killer T cell lymphoma

J Xiong, BW Cui, N Wang, YT Dai, H Zhang, CF Wang… - Cancer Cell, 2020 - cell.com
Natural killer/T cell lymphoma (NKTCL) is an aggressive and heterogeneous entity of non-
Hodgkin lymphoma, strongly associated with Epstein-Barr virus (EBV) infection. To identify …

What we should know about natural killer/T‐cell lymphomas

J Xiong, W Zhao - Hematological oncology, 2019 - Wiley Online Library
Natural‐killer/T cell lymphoma (NKTCL) is the most common extranodal lymphoma with
highly aggressive clinical outcome. System biology techniques provide novel insights into …

Advances in multiple omics of natural-killer/T cell lymphoma

J Xiong, WL Zhao - Journal of hematology & oncology, 2018 - Springer
Natural-killer/T cell lymphoma (NKTCL) represents the most common subtype of extranodal
lymphoma with aggressive clinical behavior. Prevalent in Asians and South Americans, the …

Non-coding RNAs in natural killer/T-cell lymphoma

M Mei, M Zhang - Frontiers in Oncology, 2019 - frontiersin.org
Natural killer/T-cell lymphoma (NKTCL) is a rare and aggressive subtype of non-Hodgkin's
lymphoma that is associated with a poor outcome. Non-coding RNAs (ncRNAs), which …

Epigenetic aberrations in natural killer/T-cell lymphoma: diagnostic, prognostic and therapeutic implications

C Küçük, J Wang, Y Xiang… - Therapeutic Advances in …, 2020 - journals.sagepub.com
Natural killer/T-cell lymphoma (NKTCL) is an aggressive malignancy that usually presents in
the upper aerodigestive tract. This malignancy shows substantial geographic variability in …

Update on molecular diagnosis in extranodal NK/T-cell lymphoma and its role in the era of personalized medicine

KH Sun, YT Wong, KM Cheung, C Yuen, YT Chan… - Diagnostics, 2022 - mdpi.com
Natural killer (NK)/T-cell lymphoma (NKTCL) is an aggressive malignancy with unique
epidemiological, histological, molecular, and clinical characteristics. It occurs in two …

The genomics and molecular biology of natural killer/T-cell lymphoma: opportunities for translation

S De Mel, GST Soon, Y Mok, TH Chung… - International Journal of …, 2018 - mdpi.com
Extranodal NK/T-cell lymphoma, nasal type (ENKTL), is an aggressive malignancy with a
poor prognosis. While the introduction of L-asparaginase in the treatment of this disease has …

Breaking down the barriers to define and treat NK/T cell lymphoma

B Mundy-Bosse, DM Weinstock - Cancer Cell, 2020 - cell.com
In this issue of Cancer Cell, Xiong and colleagues describe the genomic and transcriptional
landscape of natural killer/T cell lymphoma (NKTCL), a rare form of non-Hodgkin's …

Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression

Z Chen, H Huang, H Hong, H Huang, H Weng, L Yu… - Genome Medicine, 2024 - Springer
Background Natural killer/T cell lymphoma (NKTCL) is a clinically and genetically
heterogeneous disease with poor prognosis. Genome sequencing and mutation …