Improved precision of QTL mapping using a nonlinear Bayesian method in a multi-breed population leads to greater accuracy of across-breed genomic predictions
Background Genomic selection is increasingly widely practised, particularly in dairy cattle.
However, the accuracy of current predictions using GBLUP (genomic best linear unbiased …
However, the accuracy of current predictions using GBLUP (genomic best linear unbiased …
On the use of whole-genome sequence data for across-breed genomic prediction and fine-scale mapping of QTL
T Meuwissen, I van den Berg, M Goddard - Genetics Selection Evolution, 2021 - Springer
Background Whole-genome sequence (WGS) data are increasingly available on large
numbers of individuals in animal and plant breeding and in human genetics through second …
numbers of individuals in animal and plant breeding and in human genetics through second …
Impact of QTL properties on the accuracy of multi-breed genomic prediction
Background Although simulation studies show that combining multiple breeds in one
reference population increases accuracy of genomic prediction, this is not always confirmed …
reference population increases accuracy of genomic prediction, this is not always confirmed …
Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits
IM MacLeod, PJ Bowman, CJ Vander Jagt… - BMC genomics, 2016 - Springer
Background Dense SNP genotypes are often combined with complex trait phenotypes to
map causal variants, study genetic architecture and provide genomic predictions for …
map causal variants, study genetic architecture and provide genomic predictions for …
A multi-trait Bayesian method for mapping QTL and genomic prediction
Background Genomic prediction and quantitative trait loci (QTL) mapping typically analyze
one trait at a time but this may ignore the possibility that one polymorphism affects multiple …
one trait at a time but this may ignore the possibility that one polymorphism affects multiple …
Within-and across-breed genomic prediction using whole-genome sequence and single nucleotide polymorphism panels
OOM Iheshiulor, JA Woolliams, X Yu… - Genetics Selection …, 2016 - Springer
Background Currently, genomic prediction in cattle is largely based on panels of about 54k
single nucleotide polymorphisms (SNPs). However with the decreasing costs of and current …
single nucleotide polymorphisms (SNPs). However with the decreasing costs of and current …
Combining mouse mammary gland gene expression and comparative mapping for the identification of candidate genes for QTL of milk production traits in cattle
M Ron, G Israeli, E Seroussi, JI Weller, JP Gregg… - BMC genomics, 2007 - Springer
Background Many studies have found segregating quantitative trait loci (QTL) for milk
production traits in different dairy cattle populations. However, even for relatively large …
production traits in different dairy cattle populations. However, even for relatively large …
Accuracy of genomic breeding values in multi-breed dairy cattle populations
BJ Hayes, PJ Bowman, AC Chamberlain… - Genetics Selection …, 2009 - Springer
Background Two key findings from genomic selection experiments are 1) the reference
population used must be very large to subsequently predict accurate genomic estimated …
population used must be very large to subsequently predict accurate genomic estimated …
[HTML][HTML] Predicting the effect of reference population on the accuracy of within, across, and multibreed genomic prediction
I Van den Berg, THE Meuwissen, IM MacLeod… - Journal of dairy …, 2019 - Elsevier
Genomic prediction is widely used to select candidates for breeding. Size and composition
of the reference population are important factors influencing prediction accuracy. In Holstein …
of the reference population are important factors influencing prediction accuracy. In Holstein …
Genomic selection in French dairy cattle
D Boichard, F Guillaume, A Baur… - Animal Production …, 2012 - CSIRO Publishing
Genomic selection is implemented in French Holstein, Montbéliarde, and Normande breeds
(70%, 16% and 12% of French dairy cows). A characteristic of the model for genomic …
(70%, 16% and 12% of French dairy cows). A characteristic of the model for genomic …