[HTML][HTML] Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications
K Harb, E Magrinelli, CS Nicolas, N Lukianets… - Elife, 2016 - elifesciences.org
During cortical development, the identity of major classes of long-distance projection
neurons is established by the expression of molecular determinants, which become …
neurons is established by the expression of molecular determinants, which become …
[HTML][HTML] Ctip1 regulates the balance between specification of distinct projection neuron subtypes in deep cortical layers
The molecular linkage between neocortical projection neuron subtype and area
development, which enables the establishment of functional areas by projection neuron …
development, which enables the establishment of functional areas by projection neuron …
The determination of projection neuron identity in the developing cerebral cortex
DP Leone, K Srinivasan, B Chen, E Alcamo… - Current opinion in …, 2008 - Elsevier
Here we review the mechanisms that determine projection neuron identity during cortical
development. Pyramidal neurons in the mammalian cerebral cortex can be classified into …
development. Pyramidal neurons in the mammalian cerebral cortex can be classified into …
Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex
WL McKenna, CF Ortiz-Londono… - Proceedings of the …, 2015 - National Acad Sciences
Generation of distinct cortical projection neuron subtypes during development relies in part
on repression of alternative neuron identities. It was reported that the special AT-rich …
on repression of alternative neuron identities. It was reported that the special AT-rich …
Lmo4 and Clim1 Progressively Delineate Cortical Projection Neuron Subtypes during Development
E Azim, SJ Shnider, GY Cederquist, US Sohur… - Cerebral …, 2009 - academic.oup.com
Molecular controls over the development of the exceptional neuronal subtype diversity of the
cerebral cortex are now beginning to be identified. The initial subtype fate decision early in …
cerebral cortex are now beginning to be identified. The initial subtype fate decision early in …
Lmo4 establishes rostral motor cortex projection neuron subtype diversity
GY Cederquist, E Azim, SJ Shnider… - Journal of …, 2013 - Soc Neuroscience
The mammalian neocortex is parcellated into anatomically and functionally distinct areas.
The establishment of area-specific neuronal diversity and circuit connectivity enables distinct …
The establishment of area-specific neuronal diversity and circuit connectivity enables distinct …
Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution
A unique combination of transcription factor expression and projection neuron identity
demarcates each layer of the cerebral cortex. During mouse and human cortical …
demarcates each layer of the cerebral cortex. During mouse and human cortical …
The specification of cortical subcerebral projection neurons depends on the direct repression of TBR1 by CTIP1/BCL11a
J Cánovas, FA Berndt, H Sepúlveda… - Journal of …, 2015 - Soc Neuroscience
The acquisition of distinct neuronal fates is fundamental for the function of the cerebral
cortex. We find that the development of subcerebral projections from layer 5 neurons in the …
cortex. We find that the development of subcerebral projections from layer 5 neurons in the …
Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes
WE Heavner, S Ji, JH Notwell… - Proceedings of the …, 2020 - National Acad Sciences
We are only just beginning to catalog the vast diversity of cell types in the cerebral cortex.
Such categorization is a first step toward understanding how diversification relates to …
Such categorization is a first step toward understanding how diversification relates to …
[HTML][HTML] Satb2 regulates callosal projection neuron identity in the developing cerebral cortex
EA Alcamo, L Chirivella, M Dautzenberg, G Dobreva… - Neuron, 2008 - cell.com
Satb2 is a DNA-binding protein that regulates chromatin organization and gene expression.
In the developing brain, Satb2 is expressed in cortical neurons that extend axons across the …
In the developing brain, Satb2 is expressed in cortical neurons that extend axons across the …