[HTML][HTML] Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications

K Harb, E Magrinelli, CS Nicolas, N Lukianets… - Elife, 2016 - elifesciences.org
During cortical development, the identity of major classes of long-distance projection
neurons is established by the expression of molecular determinants, which become …

[HTML][HTML] Ctip1 regulates the balance between specification of distinct projection neuron subtypes in deep cortical layers

MB Woodworth, LC Greig, KX Liu, GC Ippolito… - Cell reports, 2016 - cell.com
The molecular linkage between neocortical projection neuron subtype and area
development, which enables the establishment of functional areas by projection neuron …

The determination of projection neuron identity in the developing cerebral cortex

DP Leone, K Srinivasan, B Chen, E Alcamo… - Current opinion in …, 2008 - Elsevier
Here we review the mechanisms that determine projection neuron identity during cortical
development. Pyramidal neurons in the mammalian cerebral cortex can be classified into …

Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex

WL McKenna, CF Ortiz-Londono… - Proceedings of the …, 2015 - National Acad Sciences
Generation of distinct cortical projection neuron subtypes during development relies in part
on repression of alternative neuron identities. It was reported that the special AT-rich …

Lmo4 and Clim1 Progressively Delineate Cortical Projection Neuron Subtypes during Development

E Azim, SJ Shnider, GY Cederquist, US Sohur… - Cerebral …, 2009 - academic.oup.com
Molecular controls over the development of the exceptional neuronal subtype diversity of the
cerebral cortex are now beginning to be identified. The initial subtype fate decision early in …

Lmo4 establishes rostral motor cortex projection neuron subtype diversity

GY Cederquist, E Azim, SJ Shnider… - Journal of …, 2013 - Soc Neuroscience
The mammalian neocortex is parcellated into anatomically and functionally distinct areas.
The establishment of area-specific neuronal diversity and circuit connectivity enables distinct …

Differential timing of a conserved transcriptional network underlies divergent cortical projection routes across mammalian brain evolution

A Paolino, LR Fenlon, P Kozulin… - Proceedings of the …, 2020 - National Acad Sciences
A unique combination of transcription factor expression and projection neuron identity
demarcates each layer of the cerebral cortex. During mouse and human cortical …

The specification of cortical subcerebral projection neurons depends on the direct repression of TBR1 by CTIP1/BCL11a

J Cánovas, FA Berndt, H Sepúlveda… - Journal of …, 2015 - Soc Neuroscience
The acquisition of distinct neuronal fates is fundamental for the function of the cerebral
cortex. We find that the development of subcerebral projections from layer 5 neurons in the …

Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes

WE Heavner, S Ji, JH Notwell… - Proceedings of the …, 2020 - National Acad Sciences
We are only just beginning to catalog the vast diversity of cell types in the cerebral cortex.
Such categorization is a first step toward understanding how diversification relates to …

[HTML][HTML] Satb2 regulates callosal projection neuron identity in the developing cerebral cortex

EA Alcamo, L Chirivella, M Dautzenberg, G Dobreva… - Neuron, 2008 - cell.com
Satb2 is a DNA-binding protein that regulates chromatin organization and gene expression.
In the developing brain, Satb2 is expressed in cortical neurons that extend axons across the …