Molecular mechanisms of HPV induced carcinogenesis in head and neck

T Rampias, C Sasaki, A Psyrri - Oral oncology, 2014 - Elsevier
A growing subgroup of oropharyngeal cancers is initiated by infection with high-risk human
papillomaviruses (HPVs). In parallel to mounting epidemiological evidence, solid …

Human papillomavirus in oropharyngeal cancer: The changing face of a disease

J Mallen-St Clair, M Alani, MB Wang… - Biochimica et Biophysica …, 2016 - Elsevier
The last decade has brought about an unexpected rise in oropharyngeal squamous cell
carcinoma (OPSCC) primarily in white males from the ages of 40–55 years, with limited …

[HTML][HTML] Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer

F Faraji, M Zaidi, C Fakhry, DA Gaykalova - Microbes and infection, 2017 - Elsevier
This review examines the general cellular and molecular underpinnings of human
papillomavirus (HPV)-related carcinogenesis in the context of head and neck squamous cell …

HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis

C Pan, N Issaeva, WG Yarbrough - Cancers of the head & neck, 2018 - Springer
Understanding of oropharyngeal squamous cell carcinoma has significantly progressed
over the last decades, and the concept that this disease can be subdivided into two distinct …

Human papillomavirus and oropharynx cancer: biology, detection and clinical implications

CT Allen, JS Lewis Jr, SK El‐Mofty… - The …, 2010 - Wiley Online Library
Objectives: To review evidence for the role of human papillomavirus (HPV) in the etiology of
oropharyngeal cancers, methods of viral detection, and the resulting clinical implications …

Impact of HPV in oropharyngeal cancer

L Marklund, L Hammarstedt - Journal of oncology, 2011 - Wiley Online Library
The incidence of oropharyngeal cancers has increased in the western world and Human
Papilloma Virus (HPV) has been recognised as a risk factor in the last decades. During the …

Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications

PT Hennessey, WH Westra… - Journal of dental …, 2009 - journals.sagepub.com
Over the past 20 years, high-risk human papilloma-virus (HPV) infection has been
established as a risk factor for developing head and neck squamous cell carcinoma …

Biology of human papillomavirus–related oropharyngeal cancer

JD Howard, CH Chung - Seminars in radiation oncology, 2012 - Elsevier
Recent data show that human papillomavirus–positive oropharyngeal cancer (OPC) has a
distinct biological and clinical behavior compared with human papillomavirus–negative …

The role of human papillomavirus in the pathogenesis of head & neck squamous cell carcinoma: an overview

G Pannone, A Santoro, S Papagerakis… - Infectious agents and …, 2011 - Springer
Cancer statistics report an increased incidence of OSCC and OPSCC around the world.
Though improvements in screening and early diagnosis have dramatically reduced the …

Virology and molecular pathogenesis of HPV (human papillomavirus) associated oropharyngeal squamous cell carcinoma

DL Miller, MD Puricelli, MS Stack - Biochemical Journal, 2012 - portlandpress.com
The current literature fully supports HPV (human papillomavirus)-associated OPSCC
(oropharyngeal squamous cell carcinoma) as a unique clinical entity. It affects an …