Epidemiologic and genetic aspects of spina bifida and other neural tube defects
KS Au, A Ashley‐Koch… - Developmental disabilities …, 2010 - Wiley Online Library
The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …
births with almost equal frequencies between two major categories: anencephaly and spina …
Epidemiology of neural tube defects
LE Mitchell - American Journal of Medical Genetics Part C …, 2005 - Wiley Online Library
The epidemiological investigation of the common open neural tube defects (NTDs),
anencephaly, and spina bifida, has a long history. The most significant finding from these …
anencephaly, and spina bifida, has a long history. The most significant finding from these …
Proportion of neural tube defects attributable to known risk factors
BACKGROUND Recognized risk factors for neural tube defects (NTDs) poorly predict
population‐level NTD risk. However, the proportion of NTDs that can be attributed to these …
population‐level NTD risk. However, the proportion of NTDs that can be attributed to these …
Further evidence for a maternal genetic effect and a sex‐influenced effect contributing to risk for human neural tube defects
KL Deak, DG Siegel, TM George… - … Research Part A …, 2008 - Wiley Online Library
BACKGROUND: Neural tube defects (NTDs), including spina bifida and anencephaly, are
the second most common birth defect with an incidence of 1/1000. Genetic factors are …
the second most common birth defect with an incidence of 1/1000. Genetic factors are …
Neural tube defects
NDE Greene, AJ Copp - Annual review of neuroscience, 2014 - annualreviews.org
Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …
defects of the central nervous system that originate during embryonic development when the …
Mouse models for neural tube closure defects
DM Juriloff, MJ Harris - Human molecular genetics, 2000 - academic.oup.com
Neural tube closure defects (NTDs), in particular anencephaly and spina bifida, are common
human birth defects (1 in 1000), their genetics is complex and their risk is reduced by …
human birth defects (1 in 1000), their genetics is complex and their risk is reduced by …
Genetics of human neural tube defects
Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …
involves multiple genes and environmental factors. Although more than 200 genes are …
Human neural tube defects: developmental biology, epidemiology, and genetics
ER Detrait, TM George, HC Etchevers, JR Gilbert… - Neurotoxicology and …, 2005 - Elsevier
Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …
Genetic basis of neural tube defects
AG Bassuk, Z Kibar - Seminars in pediatric neurology, 2009 - Elsevier
Neural tube defects (NTDs) represent a common group of severe congenital malformations
of the central nervous system. They result from failure of neural tube closure during early …
of the central nervous system. They result from failure of neural tube closure during early …
Epidemiologic characteristics of phenotypically distinct neural tube defects among 0.7 million California births, 1983–1987
GM Shaw, NG Jensvold, CR Wasserman… - Teratology, 1994 - Wiley Online Library
Isolated neural tube defects (NTDs) appear to have different risk factors compared to
nonisolated NTDs. To extend those observations, we explored routinely collected child and …
nonisolated NTDs. To extend those observations, we explored routinely collected child and …