The thymus is a primary lymphoid organ in which bone marrow-derived T cell precursors
undergo a complex maturation process in the context of the thymic microenvironment …

Intrathymic T‐cell Differentiation is essentially driven by the thymic microenvironment, a
tridimensional network formed by thymic epithelial cells and to a lesser extent, dendritic …

Cell adhesion, migration, differentiation and survival or death is amongst a large spectrum of
biological responses that can be elicited by ligation of extracellular matrix components to …

The thymus gland is a central lymphoid organ in which bone marrow-derived T cell
precursors undergo maturation, eventually leading to the migration of positively selected …

Thymocyte differentiation is the process by which bone marrow-derived precursors enter the
thymus, proliferate, rearrange the genes and express the corresponding T cell receptors …

Much debate has been generated about the existence of thymic nurse cells within the
thymus. Until now, the authenticity of an epithelial cell capable of internalizing developing …

The thymus plays a crucial role in the development of T lymphocytes providing an inductive
microenvironment in which committed progenitors undergo proliferation, T-cell receptor …

We previously showed that, in the context of thymic epithelial cells, thymocyte migration is
partially controlled by extracellular matrix (ECM)-mediated interactions. Herein we evaluated …

The thymic microenvironment plays a key role in the intrathymic T-cell differentiation. It is
composed of a tridimensional network of epithelial cells whose physiology is controlled by …

Thymic nurse cells (TNCs) represent a unique microenvironment in the thymus for MHC
restriction and T cell repertoire selection composed of a cortical epithelial cell surrounding …