[HTML][HTML] A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex

MMC Lam, RR Wick, SC Watts, LT Cerdeira… - Nature …, 2021 - nature.com
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …

Genomic surveillance framework and global population structure for Klebsiella pneumoniae

MMC Lam, RR Wick, SC Watts, LT Cerdeira, KL Wyres… - BioRxiv, 2020 - biorxiv.org
ABSTRACT K. pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, community-acquired liver abscess and urinary tract infections, and is …

[HTML][HTML] Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

Rapid Genomic Characterization and Global Surveillance of Klebsiella Using Pathogenwatch

S Argimón, S David, A Underwood… - Clinical Infectious …, 2021 - academic.oup.com
Background Klebsiella species, including the notable pathogen K. pneumoniae, are
increasingly associated with antimicrobial resistance (AMR). Genome-based surveillance …

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

KE Holt, H Wertheim, RN Zadoks… - Proceedings of the …, 2015 - National Acad Sciences
Klebsiella pneumoniae is now recognized as an urgent threat to human health because of
the emergence of multidrug-resistant strains associated with hospital outbreaks and …

[HTML][HTML] Whole genome sequencing reveals high-resolution epidemiological links between clinical and environmental Klebsiella pneumoniae

C Runcharoen, D Moradigaravand, B Blane… - Genome medicine, 2017 - Springer
Background Klebsiella pneumoniae is a gram-negative bacterial species capable of
occupying a broad range of environmental and clinical habitats. Known as an opportunistic …

Whole-genome sequencing of human clinical Klebsiella pneumoniae isolates reveals misidentification and misunderstandings of Klebsiella pneumoniae, Klebsiella …

SW Long, SE Linson, M Ojeda Saavedra, C Cantu… - Msphere, 2017 - Am Soc Microbiol
Klebsiella pneumoniae is a major threat to public health, causing significant morbidity and
mortality worldwide. The emergence of highly drug-resistant strains is particularly …

Integrated chromosomal and plasmid sequence analyses reveal diverse modes of carbapenemase gene spread among Klebsiella pneumoniae

S David, V Cohen, S Reuter… - Proceedings of the …, 2020 - National Acad Sciences
Molecular and genomic surveillance systems for bacterial pathogens currently rely on
tracking clonally evolving lineages. By contrast, plasmids are usually excluded or analyzed …

[HTML][HTML] Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

CL Gorrie, M Mirčeta, RR Wick, LM Judd… - Nature …, 2022 - nature.com
Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases …

[HTML][HTML] Genomic analysis of the international high-risk clonal lineage Klebsiella pneumoniae sequence type 395

ER Shaidullina, M Schwabe, T Rohde… - Genome Medicine, 2023 - Springer
Background Klebsiella pneumoniae, which is frequently associated with hospital-and
community-acquired infections, contains multidrug-resistant (MDR), hypervirulent (hv), non …