[HTML][HTML] The first line of defense: the effects of alcohol on post-burn intestinal barrier, immune cells, and microbiome

AM Hammer, NL Morris, ZM Earley… - Alcohol research …, 2015 - ncbi.nlm.nih.gov
Alcohol (ethanol) is one of the most globally abused substances, and is one of the leading
causes of premature death in the world. As a result of its complexity and direct contact with …

[HTML][HTML] Alcohol and gut-derived inflammation

F Bishehsari, E Magno, G Swanson… - Alcohol research …, 2017 - ncbi.nlm.nih.gov
In large amounts, alcohol and its metabolites can overwhelm the gastrointestinal tract (GI)
and liver and lead to damage both within the GI and in other organs. Specifically, alcohol …

Alcohol and the Intestine

S Patel, R Behara, GR Swanson, CB Forsyth, RM Voigt… - Biomolecules, 2015 - mdpi.com
Alcohol abuse is a significant contributor to the global burden of disease and can lead to
tissue damage and organ dysfunction in a subset of alcoholics. However, a subset of …

Impact of drinking alcohol on gut microbiota: Recent perspectives on ethanol and alcoholic beverage

E Lee, JE Lee - Current opinion in food science, 2021 - Elsevier
Excessive alcohol intake is a leading cause of morbidity and mortality worldwide.
Perspective of alcohol-associated disease development is shifting, from the traditional …

Summary of the 2019 alcohol and immunology research interest group (AIRIG) meeting: Alcohol-mediated mechanisms of multiple organ injury

RH McMahan, M Afshar, AM Amedee, F Bishehsari… - Alcohol, 2020 - Elsevier
Abstract On November 15, 2019, the 24th annual Alcohol and Immunology Research
Interest Group (AIRIG) meeting was held as a satellite conference during the annual Society …

[HTML][HTML] The gastrointestinal microbiome: alcohol effects on the composition of intestinal microbiota

PA Engen, SJ Green, RM Voigt, CB Forsyth… - Alcohol research …, 2015 - ncbi.nlm.nih.gov
The excessive use of alcohol is a global problem causing many adverse pathological health
effects and a significant financial health care burden. This review addresses the effect of …

[HTML][HTML] A perspective of intestinal immune-microbiome interactions in alcohol-associated liver disease

R Bruellman, C Llorente - International journal of biological …, 2021 - ncbi.nlm.nih.gov
Uncovering the intricacies of the gut microbiome and how it interacts with the host immune
system has opened up pathways in the search for the treatment of disease conditions …

Chronic alcohol exposure renders epithelial cells vulnerable to bacterial infection

S Wood, R Pithadia, T Rehman, L Zhang, J Plichta… - PloS one, 2013 - journals.plos.org
Despite two centuries of reports linking alcohol consumption with enhanced susceptibility to
bacterial infections and in particular gut-derived bacteria, there have been no studies or …

Intestinal microbial products from alcohol‐fed mice contribute to intestinal permeability and peripheral immune activation

DR Samuelson, M Gu, JE Shellito… - Alcoholism: Clinical …, 2019 - Wiley Online Library
Background Alcohol use causes significant disruption of intestinal microbial communities,
yet exactly how these dysbiotic communities interact with the host is unclear. We sought to …

Microbiota protects mice against acute alcohol‐induced liver injury

P Chen, Y Miyamoto, M Mazagova… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background Our aim is to investigate the physiological relevance of the intestinal microbiota
in alcohol‐induced liver injury. Chronic alcohol abuse is associated with intestinal bacterial …