Next generation sequencing: chemistry, technology and applications

P Hui - Chemical Diagnostics: From Bench to Bedside, 2014 - Springer
High-throughput next generation sequencing (NGS) has been quickly adapted into many
aspects of biomedical research and begun to engage with the clinical practice. The latter …

[HTML][HTML] Next-generation sequencing for cancer diagnostics: a practical perspective

C Meldrum, MA Doyle, RW Tothill - The Clinical Biochemist …, 2011 - ncbi.nlm.nih.gov
Next-generation sequencing (NGS) is arguably one of the most significant technological
advances in the biological sciences of the last 30 years. The second generation sequencing …

Next-generation sequencing and its applications in molecular diagnostics

Z Su, B Ning, H Fang, H Hong, R Perkins… - Expert review of …, 2011 - Taylor & Francis
DNA sequencing is a powerful approach for decoding a number of human diseases,
including cancers. The advent of next-generation sequencing (NGS) technologies has …

Next-generation sequencing: from basic research to diagnostics

KV Voelkerding, SA Dames, JD Durtschi - Clinical chemistry, 2009 - academic.oup.com
Background: For the past 30 years, the Sanger method has been the dominant approach
and gold standard for DNA sequencing. The commercial launch of the first massively …

Next-generation sequencing: a new revolution in molecular diagnostics?

EP Diamandis - Clinical chemistry, 2009 - academic.oup.com
In 1980, Fred Sanger and Walter Gilbert were awarded the Nobel Prize in Chemistry for
discovering novel ways for sequencing nucleic acids. In 2003, the human genome …

Landscape of next-generation sequencing technologies

TP Niedringhaus, D Milanova, MB Kerby… - Analytical …, 2011 - ACS Publications
DNA sequencing is in the throes of an enormous technolog-ical shift marked by dramatic
throughput increases, a precipitously dropping per-base cost of raw sequence, and an …

Next-generation sequencing technology: current trends and advancements

H Satam, K Joshi, U Mangrolia, S Waghoo, G Zaidi… - Biology, 2023 - mdpi.com
Simple Summary Next-generation sequencing (NGS) is a powerful tool used in genomics
research. NGS can sequence millions of DNA fragments at once, providing detailed …

The application of next-generation sequencing technologies to drug discovery and development

PM Woollard, NAL Mehta, JJ Vamathevan… - Drug discovery today, 2011 - Elsevier
Next-generation sequencing (NGS) technologies represent a paradigm shift in sequencing
capability. The technology has already been extensively applied to biological research …

Next-generation sequencing—an overview of the history, tools, and “Omic” applications

JK Kulski - Next generation sequencing-advances, applications …, 2016 - books.google.com
Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

Overview of technical aspects and chemistries of next-generation sequencing

IS Hagemann - Clinical genomics, 2015 - Elsevier
Clinical genomic testing has been made possible by the development of “next-generation”
sequencing (NGS) technologies that allow large quantities of nucleic acid sequence to be …