Abstract Estrogen-related receptors (ERR), ERR alpha (ERRα) and ERR gamma (ERRγ),
are orphan nuclear receptors implicated in breast cancer that function similarly in the …

Estrogen-related receptor alpha (ERRα) is an orphan member of the nuclear receptor family
of transcription factors. In addition to its function as a metabolic regulator, ERRα has been …

Background One-third of estrogen (ER+) and/or progesterone receptor-positive (PGR+)
breast tumors treated with Tamoxifen (TAM) do not respond to initial treatment, and the …

Expression of estrogen-related receptor α (ERRα) has recently been shown to carry
negative prognostic significance in breast and ovarian cancers. The specific role of this …

Breast cancer is primarily a hormone-dependent tumor that can be regulated by status of
steroid hormones including estrogen and progesterone. Estrogen-related receptors (ERRs) …

Estrogen receptors are important regulators of the growth of breast tumors. Three different
receptors for estrogens have been identified in breast tumors, two nuclear receptors, ERα …

The importance of estrogen-related receptors (ERRs) in human breast cancer was assessed
by comparing their mRNA profiles with established clinicopathological indicators and mRNA …

The estrogen-related receptor α (ERRα) is an orphan member of the nuclear receptor
superfamily of transcription factors whose activity is regulated by the expression level and/or …

A genomic signature designed to assess the activity of the estrogen-related receptor alpha
(ERRα) was used to profile more than 800 breast tumors, revealing a shorter disease-free …

Cancer is perhaps the fastest growing non-communicable disease in the human population
worldwide. Although the molecular mechanism of cancer initiation and progression is known …