The role of surgery in the management of patients with sporadic (not part of multiple
endocrine neoplasia type 1) Zollinger–Ellison syndrome (ZES) is controversial. In this …

Objective: Highlight unresolved controversies in the management of Zollinger-Ellison
syndrome (ZES). Summary Background Data: Recent studies have resolved some of the …

About 30% of patients with MEN1 develop a Zollinger-Ellison syndrome. Meanwhile it is well
established that the causative gastrinomas are almost exclusively localized in the …

Zollinger–Ellison syndrome (ZES) is a clinical syndrome with severe peptic ulcer disease
and diarrhea caused by gastric acid hypersecretion secondary to a neuroendocrine tumour …

Gastrinoma is the most frequent functional pancreaticoduodenal endocrine tumor in patients
with multiple endocrine neoplasia type 1 (MEN1) and one major determinant of mortality in …

With the development of effective drugs to control the gastric acid hypersecretion in Zollinger-
Ellison syndrome (ZES) patients, the role of surgery has changed. In 1982, Brennan …

Enterochromaffin-like (ECL) tumors are documented in patients with hypergastrinemia
secondary to chronic atrophic gastritis or with Zollinger-Ellison syndrome and multiple …

During the three decades since the recognition of the Zollinger‐Ellison syndrome (ZES),
major progress has been made in the diagnosis and treatment of this disease. However, the …

Background and Methods The role of surgery in patients with the Zollinger–Ellison
syndrome is controversial. To determine the efficacy of surgery in patients with this …

Simple Summary Approximately 30% of patients with multiple endocrine neoplasia type 1
(MEN1) develop the Zollinger–Ellison syndrome (ZES), caused by solitary or multiple …